Hepatotoxicity associated with antiepileptic drugs

E Björnsson - Acta Neurologica Scandinavica, 2008 - Wiley Online Library
Background–Drug‐induced liver injury associated with antiepileptic drugs (AED) is well
recognized. The frequency of the most common AED is rare but the consequences can be …

Oxcarbazepine: a review of its pharmacology and therapeutic potential in epilepsy, trigeminal neuralgia and affective disorders

SM Grant, D Faulds - Drugs, 1992 - Springer
Synopsis Oxcarbazepine is the 10-keto analogue of carbamazepine but has a distinct
pharmacokinetic profile. In contrast to the oxidative metabolism of carbamazepine …

Degradation of carbamazepine by Trametes versicolor in an air pulsed fluidized bed bioreactor and identification of intermediates

A Jelic, C Cruz-Morató, E Marco-Urrea, M Sarrà… - Water research, 2012 - Elsevier
The paper describes the aerobic degradation of carbamazepine (CBZ), an anti-epileptic
drug widely found in aquatic environment, from Erlenmeyer flask to bioreactor by the white …

Antidepressant effects of carbamazepine.

RM Post, TW Uhde, PP Roy-Byrne… - The American journal of …, 1986 - europepmc.org
Thirty-five depressed patients diagnosed by DSM-III criteria participated in a double-blind
study of the acute antidepressant effects of the anticonvulsant carbamazepine, at average …

Carbamazepine in aggressive children with conduct disorder: a double-blind and placebo-controlled study

JE Cueva, JE Overall, AM Small, JL Armenteros… - Journal of the American …, 1996 - Elsevier
OBJECTIVE: To assess critically the short-term efficacy and safety of carbamazepine in the
reduction of aggressiveness in children with diagnosed conduct disorder. METHOD …

Comparison of oxcarbazepine and carbamazepine: a double-blind study

KJ Reinikainen, T Keranen, T Halonen, H Komulainen… - Epilepsy research, 1987 - Elsevier
The antiepileptic efficacy and side-effects of oxcarbazepine (OXC), a new carbamazepine
derivate, were evaluated in a doubleblind study. Forty ambulatory epileptics with …

Carbamazepine versus oxazepam in the treatment of alcohol withdrawal: a double-blind study

CH Stuppaeck, R Pycha, C Miller… - Alcohol and …, 1992 - academic.oup.com
The use of more than 130 drugs and drug combinations against the alcohol withdrawal
syndrome reflects the fact that views on its treatment are far from being unequivocal …

Oxcarbazepine: a new drug in the management of intractable trigeminal neuralgia.

JM Zakrzewska, PN Patsalos - Journal of Neurology, Neurosurgery & …, 1989 - jnnp.bmj.com
The efficacy and tolerability of oxcarbazepine, a keto derivative of carbamazepine, has been
assessed in six patients (two males, four females; mean age 61 years, range 42-77), with …

Oxcarbazepine, an antiepileptic agent

MM Kalis, NA Huff - Clinical therapeutics, 2001 - Elsevier
Background: Epilepsy is a common neurologic condition. Many of the currently approved
pharmacologic agents for its treatment are associated with numerous adverse drug …

Efficacy and safety of eslicarbazepine acetate as add‐on treatment in patients with focal‐onset seizures: integrated analysis of pooled data from double‐blind phase III …

A Gil‐Nagel, C Elger, E Ben‐Menachem, P Halász… - …, 2013 - Wiley Online Library
Purpose: To evaluate the efficacy and safety profile of eslicarbazepine acetate (ESL) added
to stable antiepileptic therapy in adults with partial‐onset seizures. Methods: Data from …