Surgical resection of cancer remains an important treatment modality. Despite advances in
preoperative imaging, surgery itself is primarily guided by the surgeon's ability to locate …

Paradigm shifts in surgery arise when surgeons are empowered to perform surgery faster,
better and less expensively than current standards. Optical imaging that exploits invisible …

Bladder cancer is a heterogeneous disease with a variable natural history. At one end of the
spectrum, low-grade Ta tumors have a low progression rate and require initial endoscopic …

Abbreviations: ACF, aberrant crypt foci; ALA, 5-aminolevulinic acid; AIS4PC, tetrasulfonated
chloroaluminum phthalocyanine; antiCEA MoAb, anticarcinoembryonic antigen; BBC, basal …

Context Controversy exists regarding the therapeutic benefit and cost effectiveness of
photodynamic diagnosis (PDD) with 5-aminolevulinic acid (5-ALA) or hexyl aminolevulinate …

CONTEXT: The clinical benefit of photodynamic diagnosis (PDD) with 5-aminolevulinic acid
or hexaminolevulinate in addition to white-light cystoscopy (WLC) in bladder cancer has …

Purpose: We assessed the impact that improved detection of nonmuscle invasive bladder
cancer with hexaminolevulinate fluorescence cystoscopy may have on early recurrence …

Aminolevulinic acid (ALA), when added to many tissues, results in the accumulation of
sufficient quantities of the endogenous photosensitizer protoporphyrin IX (PpIX) via the …

Purpose: We determined if improved tumor detection using hexaminolevulinate (HAL)
fluorescence cystoscopy could lead to improved treatment in patients with bladder cancer …

Purpose: We examined the sensitivity and specificity of Hexvix (PhotoCure ASA, Oslo,
Norway) hexyl aminolevulinate (HAL) fluorescence cystoscopy in patients with superficial …