Myocardial infarctions are one of the most common forms of cardiac injury and death
worldwide. Infarctions cause immediate necrosis in a localized region of the myocardium …

Myocardial infarction is remains the leading cause of death in developed countries. Recent
data show that the composition of the extracellular matrix might differ despite similar heart …

Background: Myocardial infarction (MI) is among the leading causes of death worldwide.
Following MI, necrotic cardiomyocytes are replaced by a stiff collagen-rich scar. Compared …

Myocardial injury leads to an irreversible loss of cardiomyocytes (CM). The implantation of
human engineered heart tissue (EHT) has become a promising regenerative approach …

BACKGROUND: Apelin is an endogenous prepropeptide that regulates cardiac
homeostasis and various physiological processes. Intravenous injection has been shown to …

Imaging the structural modifications of underlying tissues is vital to monitor wound healing.
Optical coherence tomography (OCT) images high‐resolution sub‐surface information, but …

Galectin-3 (Gal-3) participates in myocardial fibrosis (MF) in a variety of ways. Inhibiting the
expression of Gal-3 can effectively interfere with MF. This study aimed to explore the value of …

We previously found that the levels of metabolite N-acetylglutamine were significantly
increased in urine samples of patients with heart failure (HF) and in coronary artery ligation …

Excessive cardiac fibrosis plays a crucial role in almost all types of heart disease. Generally,
cardiac fibrosis is a scarring process triggered in response to stress, injury, or aging and is …

Extracellular collagen remodeling is one of the central mechanisms responsible for the
structural and compositional coherence of myocardium in patients undergoing myocardial …