Non-small cell lung cancer (NSCLC) is the leading cause of death by cancer worldwide.
Despite developments in therapeutic approaches for the past few decades, the 5-year …

Primary immune thrombocytopenia is an autoimmune disease associated with a reduced
peripheral blood platelet count. The phenotype is variable with some patients suffering no …

Rheumatoid arthritis (RA) is one of more than 100 types of arthritis. This chronic autoimmune
disorder affects the lining of synovial joints in about 0.5% of people and may induce severe …

Abstract N6-methyladenosine (m6A) methylation is the most universal internal modification
in eukaryotic mRNA. With elaborate functions executed by m6A writers, erasers, and …

Gut microbiota can interact with the immune system through its metabolites. Short-chain fatty
acids (SCFAs), as one of the most abundant metabolites of the resident gut microbiota play …

Dendritic cells (DCs), the most potent antigen-presenting cells, are necessary for effective
activation of naïve T cells. DCs' immunological properties are modulated in response to …

The PD-1/PD-L1 signaling pathway plays a crucial role in cancer immune evasion, and the
use of anti-PD-1/PD-L1 antibodies represents a significant milestone in cancer …

It is being increasingly acknowledged that immune cells depend on certain metabolic traits
to perform their functions and that the extracellular environment can influence cell …

Dendritic cells (DCs) are potent antigen-presenting cells (APCs) that are essential in
mediating the body's natural and adaptive immune responses. The body can regulate the …

Dendritic cells (DCs) dictate the outcomes of tissue-specific immune responses. In the
context of autoimmune diseases, DCs instruct T cells to respond to antigens (Ags), including …