[HTML][HTML] Immunological considerations for COVID-19 vaccine strategies

M Jeyanathan, S Afkhami, F Smaill, MS Miller… - Nature Reviews …, 2020 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) is the most formidable challenge to …

[PDF][PDF] Properties of coronavirus and SARS-CoV-2

YA Malik - The Malaysian journal of pathology, 2020 - mjpath.org.my
Zoonotic coronaviruses were discovered in the 1960s. Since then pathogenic human
coronaviruses were identified beginning with the discovery of SARS-CoV in 2002. With the …

[HTML][HTML] Coronavirus envelope protein: current knowledge

D Schoeman, BC Fielding - Virology journal, 2019 - Springer
Abstract Background Coronaviruses (CoVs) primarily cause enzootic infections in birds and
mammals but, in the last few decades, have shown to be capable of infecting humans as …

COVID-19 vaccine: where are we now and where should we go?

S Soleimanpour, A Yaghoubi - Expert review of vaccines, 2021 - Taylor & Francis
Introduction The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has
currently caused the pandemic with a high progressive speed and has been considered as …

[HTML][HTML] Animal and translational models of SARS-CoV-2 infection and COVID-19

MD Johansen, A Irving, X Montagutelli, MD Tate… - Mucosal …, 2020 - nature.com
COVID-19 is causing a major once-in-a-century global pandemic. The scientific and clinical
community is in a race to define and develop effective preventions and treatments. The …

The NLRP3 inflammasome and COVID-19: Activation, pathogenesis and therapeutic strategies

N Zhao, B Di, L Xu - Cytokine & growth factor reviews, 2021 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), exhibits a wide spectrum of clinical presentations …

[HTML][HTML] Vaccines for SARS-CoV-2: lessons from other coronavirus strains

E Padron-Regalado - Infectious diseases and therapy, 2020 - Springer
The emergence of the strain of coronavirus SARS-CoV-2 (severe acute respiratory
syndrome coronavirus 2) and its impact on global health have made imperative the …

[HTML][HTML] Viral pandemics of the last four decades: pathophysiology, health impacts and perspectives

S Roychoudhury, A Das, P Sengupta, S Dutta… - International journal of …, 2020 - mdpi.com
The last four decades has witnessed some of the deadliest viral pandemics with far-reaching
consequences. These include the Human Immunodeficiency Virus (HIV)(1981), Severe …

[HTML][HTML] Coronaviruses—drug discovery and therapeutic options

A Zumla, JFW Chan, EI Azhar, DSC Hui… - Nature reviews Drug …, 2016 - nature.com
In humans, infections with the human coronavirus (HCoV) strains HCoV-229E, HCoV-OC43,
HCoV-NL63 and HCoV-HKU1 usually result in mild, self-limiting upper respiratory tract …

Coronaviruses: an overview of their replication and pathogenesis

AR Fehr, S Perlman - Coronaviruses: methods and protocols, 2015 - Springer
Abstract Coronaviruses (CoVs), enveloped positive-sense RNA viruses, are characterized
by club-like spikes that project from their surface, an unusually large RNA genome, and a …