Comet assay: a reliable tool for the assessment of DNA damage in different models

A Dhawan, M Bajpayee, D Parmar - Cell biology and toxicology, 2009 - Springer
New chemicals are being added each year to the existing burden of toxic substances in the
environment. This has led to increased pollution of ecosystems as well as deterioration of …

The Comet assay for the evaluation of genotoxic impact in aquatic environments

G Frenzilli, M Nigro, BP Lyons - Mutation research/reviews in mutation …, 2009 - Elsevier
This review considers the potential of the Comet assay (or Single Cell Gel Electrophoresis,
SCGE) to evaluate the environmental impact of genotoxins in aquatic environments. It …

[HTML][HTML] An overview of comet assay application for detecting DNA damage in aquatic animals

N Jiang, S Naz, Y Ma, Q Ullah, MZ Khan, J Wang, X Lu… - Agriculture, 2023 - mdpi.com
This review discusses several research studies that employed comet assay to evaluate the
environmental impact of genotoxins in aquatic environments. It focuses on in vivo and in situ …

The genotoxic effects of the imidacloprid-based insecticide formulation Glacoxan Imida on Montevideo tree frog Hypsiboas pulchellus tadpoles (Anura, Hylidae)

JM Pérez-Iglesias, CR de Arcaute, N Nikoloff… - Ecotoxicology and …, 2014 - Elsevier
The neonicotinoid insecticide imidacloprid (IMI) affects the insect central nervous system
and is successfully applied to control pests for a variety of agricultural crops. In the current …

Genotoxicity evaluation of the insecticide imidacloprid on circulating blood cells of Montevideo tree frog Hypsiboas pulchellus tadpoles (Anura, Hylidae) by comet and …

CR De Arcaute, JM Pérez-Iglesias, N Nikoloff… - Ecological …, 2014 - Elsevier
Acute toxicity and genotoxicity of imidacloprid (IMI) was evaluated on Hypsiboas pulchellus
(Anura: Hylidae) tadpoles exposed under laboratory conditions. A lethal effect was used as …

The comet assay in animal models: from bugs to whales–(Part 2 Vertebrates)

G Gajski, B Žegura, C Ladeira, M Novak… - … Research/Reviews in …, 2019 - Elsevier
The comet assay has become one of the methods of choice for the evaluation and
measurement of DNA damage. It is sensitive, quick to perform and relatively affordable for …

Histological changes, lipid metabolism and oxidative stress in the liver of Bufo gargarizans exposed to cadmium concentrations

C Wu, Y Zhang, L Chai, H Wang - Chemosphere, 2017 - Elsevier
Chinese toad (Bufo gargarizans) were exposed to different concentrations of cadmium (5,
50, 100, 200 and 500 μg Cd L− 1) from Gosner stage 3–42. Metamorphosis rate, body …

Toxicity of CeO2 nanoparticles at different trophic levels–effects on diatoms, chironomids and amphibians

A Bour, F Mouchet, L Verneuil, L Evariste, J Silvestre… - Chemosphere, 2015 - Elsevier
The aim of the present work is to provide wider information on the toxicity of cerium dioxide
nanoparticles (CeO 2 NPs) in aquatic environments, by studying the toxicity of two types of …

Early genotoxic effects in gill cells and haemocytes of Dreissena polymorpha exposed to cadmium, B [a] P and a combination of B [a] P and Cd

F Vincent-Hubert, A Arini, C Gourlay-Francé - Mutation Research/Genetic …, 2011 - Elsevier
The aim of this study was to assess the genotoxic potential of environmentally relevant
concentrations of Cd on the zebra mussel, an important freshwater sentinel organism, and to …

Exposures to chemical contaminants: What can we learn from reproduction and development endpoints in the amphibian toxicology literature?

S Slaby, M Marin, G Marchand, S Lemiere - Environmental pollution, 2019 - Elsevier
Environmental contamination is one of the major factors or cofactors affecting amphibian
populations. Since 2000, the number of studies conducted in laboratory conditions to …