The reactive oxygen species (ROS)-producing enzyme NADPH oxidase (NOX) was first
identified in the membrane of phagocytic cells. For many years, its only known role was in …

Reactive oxygen species (ROS) are a chemically defined group of reactive molecules
derived from molecular oxygen. ROS are involved in a plethora of processes in cells in all …

Oxidative stress defines a condition in which the prooxidant–antioxidant balance in the cell
is disturbed, resulting in DNA hydroxylation, protein denaturation, lipid peroxidation, and …

Reactive oxygen species (ROS), produced by respiratory burst oxidase homologs (RBOHs)
at the apoplast, play a key role in local and systemic cell-to-cell signaling, required for plant …

Reactive oxygen species (ROS), which were originally characterized in terms of their
harmful effects on cells and invading microorganisms, are increasingly implicated in various …

Reactive oxygen species (ROS) react preferentially with certain atoms to modulate functions
ranging from cell homeostasis to cell death. Molecular actions include both inhibition and …

Systemic signaling pathways enable multicellular organisms to prepare all of their tissues
and cells to an upcoming challenge that may initially only be sensed by a few local cells …

Although historically viewed as purely harmful, recent evidence suggests that reactive
oxygen species (ROS) function as important physiological regulators of intracellular …

This article looks back to the antioxidant/free radical field in 1994 and discusses how it has
progressed in the past 18 years. In some areas, there has been little change: the role of …

Age-related diseases such as obesity, diabetes, non-alcoholic fatty liver disease, chronic
kidney disease and cardiomyopathy are frequently associated with fibrosis. Work within the …