[PDF][PDF] Cytotoxicity, antitumoral and antimycobacterial activity of tetrazole and oxadiazole derivatives

AO De Souza, MTC Pedrosa, JB Alderete… - Die Pharmazie-An …, 2005 - researchgate.net
In this study, the antimycobacterial activity of mono and di-substituted tetrazole and
oxadiazole derivatives and their precursors was assayed on Mycobacterium tuberculosis …

Synthesis, pharmacological evaluation, molecular docking and in silico ADMET prediction of nitric oxide releasing biphenyls as anti-inflammatory agents

MG Shinde, SJ Modi, VM Kulkarni - Journal of Applied …, 2017 - japsonline.com
Abstract Various 2-(4'-methyl-N-phenyl substituted)-1, 1'-biphenyl-2-ylcarboxamido-2-
oxoethyl nitrate analogues were synthesized and evaluated for analgesic, anti-inflammatory …

Synthesis of functionalized 2′, 4-diarylbenzophenones based on site-selective Suzuki cross-coupling reactions

M Nawaz, M Adeel, MF Ibad, P Langer - Synlett, 2009 - thieme-connect.com
Thieme E-Journals - Synlett / Full Text DE EN Home Products Journals Books Book Series
Service Library Service Help Contact Portal SYNLETT Full-text search Full-text search Author …

Synthesis of functionalized 3, 4-diarylbenzophenones and 2, 4-diarylbenzophenones by site-selective suzuki and sonogashira cross-coupling reactions of bis (triflates …

RA Khera, M Nawaz, H Feist, A Villinger, P Langer - Synthesis, 2012 - thieme-connect.com
Abstract Palladium (0)-catalyzed Suzuki and Sonogashira cross-coupling reactions of the
bis (triflates) of 2, 4-and 3, 4-dihydroxybenzophenone afforded 2, 4-and 3, 4 …

Synthesis of 2′, 4‐Diarylbenzophenones through Site‐Selective Suzuki–Miyaura Reactions of Bis (triflates) of 2′, 4‐Dihydroxybenzophenones

M Nawaz, I Ullah, OUR Abid, A Villinger, P Langer - 2011 - Wiley Online Library
Synthesis of 2′,4‐Diarylbenzophenones through Site‐Selective Suzuki–Miyaura
Reactions of Bis(triflates) of 2′,4‐Dihydroxybenzophenones - Nawaz - 2011 - European …

Applications of neural networks in the medicinal chemistry field

C Ochoa, A Chana, M Stud - Current Medicinal Chemistry …, 2001 - ingentaconnect.com
Since the early nineties the number of scientific papers dealing with the applications of
artificial neural networks (ANNs) in medicinal chemistry and medicine fields has been …

Flow microcalorimetric studies of phenol and its chlorinated derivatives and a theoretical evaluation of their possible inhibition mode on Chromobacterium violaceum …

MM Basheer, PLO Volpe, C Airoldi - International journal of pharmaceutics, 2004 - Elsevier
The general belief that chemical structure determines the biological effect of drugs has led to
several techniques to establish structure–activity relationships (SAR) that is useful in the …

The 4-indolyl-2-guanidinothiazoles QSAR study of anti-ulcer activity using quantum descriptors

EG Borges, Y Takahata - Journal of Molecular Structure: THEOCHEM, 2002 - Elsevier
The QSAR modeling of the inhibitory capability of a series of 28 4-indolyl 2-
guanidinothiazoles on enzyme H+ K+-ATPase was done with empirical models based on …

Synthesis and Antileukemic Activity of Novel 2‐(4‐(2, 4‐dimethoxybenzoyl) phenoxy)‐1‐(4‐(3‐(piperidin‐4‐yl) propyl) piperidin‐1‐yl) ethanone Derivatives

K Vinaya, CV Kavitha, DS Prasanna… - Chemical Biology & …, 2012 - Wiley Online Library
A series of novel 2‐(4‐(2, 4‐dimethoxybenzoyl) phenoxy)‐1‐(4‐(3‐(piperidin‐4‐yl) propyl)
piperidin‐1‐yl) ethanone derivatives 9 (a–e) and 10 (a–g) were synthesized and …

N-(2-Benzoyl-4-chlorophenyl)-2-chloroacetamide

SM Malathy Sony, P Charles… - … Section E: Structure …, 2005 - journals.iucr.org
In the title compound, C15H11Cl2NO2, the aromatic rings are twisted by 62.2 (1)° and the
chloroacetamide moiety adopts an extended conformation. Intramolecular N—H⋯ O and N …