Overcoming cancer chemotherapy resistance by the induction of ferroptosis
Y Wang, X Wu, Z Ren, Y Li, W Zou, J Chen… - Drug Resistance …, 2023 - Elsevier
Abstract Development of resistance to chemotherapy in cancer continues to be a major
challenge in cancer management. Ferroptosis, a unique type of cell death, is mechanistically …
challenge in cancer management. Ferroptosis, a unique type of cell death, is mechanistically …
Metformin improves ovarian cancer sensitivity to paclitaxel and platinum-based drugs: a review of in vitro findings
G Tossetta - International Journal of Molecular Sciences, 2022 - mdpi.com
Ovarian cancer is one of the most dangerous gynecologic cancers worldwide, showing a
high fatality rate and recurrence due to diagnosis at an advanced stage of the disease and …
high fatality rate and recurrence due to diagnosis at an advanced stage of the disease and …
Codelivery of phytochemicals with conventional anticancer drugs in form of nanocarriers
Anticancer drugs in monotherapy are ineffective to treat various kinds of cancer due to the
heterogeneous nature of cancer. Moreover, available anticancer drugs possessed various …
heterogeneous nature of cancer. Moreover, available anticancer drugs possessed various …
Reactive oxygen species mediated apoptotic death of colon cancer cells: Therapeutic potential of plant derived alkaloids
VK Nelson, MV Nuli, J Mastanaiah… - Frontiers in …, 2023 - frontiersin.org
Colorectal cancer (CRC) is one of the most deaths causing diseases worldwide. Several risk
factors including hormones like insulin and insulin like growth factors (eg, IGF-1) have been …
factors including hormones like insulin and insulin like growth factors (eg, IGF-1) have been …
Gastrointestinal Degradation and Toxicity of Disinfection Byproducts in Drinking Water Using In Vitro Models and the Roles of Gut Microbiota
J Yin, D Li, T Zheng, B Hu, P Wang - Environmental Science & …, 2023 - ACS Publications
Disinfection byproducts (DBPs) in drinking water are mainly exposed to the human body
after oral ingestion and degradation in the gastrointestinal tract. The role of gastrointestinal …
after oral ingestion and degradation in the gastrointestinal tract. The role of gastrointestinal …
Exploring Synergistic Interactions between Natural Compounds and Conventional Chemotherapeutic Drugs in Preclinical Models of Lung Cancer
M Boța, L Vlaia, AR Jîjie, I Marcovici, F Crişan… - Pharmaceuticals, 2024 - mdpi.com
In the current work, the synergy between natural compounds and conventional
chemotherapeutic drugs is comprehensively reviewed in light of current preclinical research …
chemotherapeutic drugs is comprehensively reviewed in light of current preclinical research …
Network pharmacology-based anti-colorectal cancer activity of piperlonguminine in the ethanolic root extract of Piper longum L
Colorectal cancer (CRC) has the second highest incidence and fatality rates of any
malignancy, at 10.2 and 9.2%, respectively. Plants and plants-based products for thousands …
malignancy, at 10.2 and 9.2%, respectively. Plants and plants-based products for thousands …
Genomic-driven nutritional interventions for radiotherapy-resistant rectal cancer patient
J Southern, G Gonzalez, P Borgas, L Poynter… - Scientific Reports, 2023 - nature.com
Radiotherapy response of rectal cancer patients is dependent on a myriad of molecular
mechanisms including response to stress, cell death, and cell metabolism. Modulation of …
mechanisms including response to stress, cell death, and cell metabolism. Modulation of …
The chemo-sensitizing effect of doxorubicin of apple extract-enriched triterpenic complex on human colon adenocarcinoma and human glioblastoma cell lines
A Braciuliene, V Janulis, V Petrikaite - Pharmaceutics, 2022 - mdpi.com
Cancer cells' resistance to anticancer drugs represents a major clinical problem and the
most important failure of treatment. Combination chemotherapy is more effective than …
most important failure of treatment. Combination chemotherapy is more effective than …
NRF2 and Bip interconnection mediates resistance to the organometallic Ruthenium-Cymene Bisdemethoxycurcumin complex cytotoxicity in colon cancer cells
Organometallic ruthenium (Ru)(II)-cymene complexes display promising pharmacological
properties and might represent alternative therapeutic agents in medical applications …
properties and might represent alternative therapeutic agents in medical applications …