Molecular targeting therapies for neuroblastoma: Progress and challenges

A Zafar, W Wang, G Liu, X Wang, W Xian… - Medicinal research …, 2021 - Wiley Online Library
There is an urgent need to identify novel therapies for childhood cancers. Neuroblastoma is
the most common pediatric solid tumor, and accounts for~ 15% of childhood cancer‐related …

Neuroblastoma treatment in the post-genomic era

MR Esposito, S Aveic, A Seydel, GP Tonini - Journal of biomedical science, 2017 - Springer
Neuroblastoma is an embryonic malignancy of early childhood originating from neural crest
cells and showing heterogeneous biological, morphological, genetic and clinical …

[HTML][HTML] Genetic predisposition and chromosome instability in neuroblastoma

GP Tonini, M Capasso - Cancer and Metastasis Reviews, 2020 - Springer
Neuroblastoma (NB) is a pediatric tumor of embryonic origin. About 1–2% of all NBs are
familial cases, and genetic predisposition is suspected for the remaining cases. During the …

Nanomedicines for pediatric cancers

C Rodriguez-Nogales, Y Gonzalez-Fernandez… - ACS …, 2018 - ACS Publications
Chemotherapy protocols for childhood cancers are still problematic due to the high toxicity
associated with chemotherapeutic agents and incorrect dosing regimens extrapolated from …

[HTML][HTML] A molecular basis of tumor metastasis and current approaches to decode targeted migration-promoting events in pediatric neuroblastoma

D Corallo, M Dalla Vecchia, D Lazic… - Biochemical …, 2023 - Elsevier
Cell motility is a crucial biological process that plays a critical role in the development of
multicellular organisms and is essential for tissue formation and regeneration. However …

Diagnostic and therapeutic approaches for glioblastoma and neuroblastoma cancers using chlorotoxin nanoparticles

T Boltman, M Meyer, O Ekpo - Cancers, 2023 - mdpi.com
Simple Summary Glioblastoma multiforme (GB) and neuroblastomas (NBs) are nervous
system cancers that are difficult to diagnosis and treat. Chlorotoxin (CTX), is a peptide …

Exploring cancer cell behavior in vitro in three-dimensional multicellular bioprintable collagen-based hydrogels

DF Duarte Campos, A Bonnin Marquez, C O'Seanain… - Cancers, 2019 - mdpi.com
In vitro cancer 3D models are valuable tools to provide mechanistic insight into solid tumor
growth, invasion, and drug delivery. The 3D spheroid model of solid tumors has been the …

[HTML][HTML] Role and toxicity of radiation therapy in neuroblastoma patients: A literature review

Q Zhao, Y Liu, Y Zhang, L Meng, J Wei, B Wang… - Critical reviews in …, 2020 - Elsevier
Neuroblastoma is the most common extracranial solid tumor, arising from primitive
sympathetic ganglion cells, in pediatric patients. The unique features of neuroblastoma …

Antitumor Effects of Natural Compounds Derived from Allium sativum on Neuroblastoma: An Overview

CC Patiño-Morales, R Jaime-Cruz, C Sánchez-Gómez… - Antioxidants, 2021 - mdpi.com
Garlic (Allium sativum) has been used in alternative medicine to treat several diseases, such
as cardiovascular and neurodegenerative diseases, cancer, and hepatic diseases. Several …

Role of non-coding RNAs in neuroblastoma

AA Anoushirvani, A Jafarian Yazdi, S Amirabadi… - Cancer Gene …, 2023 - nature.com
Neuroblastoma is known as the most prevalent extracranial malignancy in childhood with a
neural crest origin. It has been widely accepted that non-coding RNAs (ncRNAs) play …