Modeling cardiac muscle fibers in ventricular and atrial electrophysiology simulations

R Piersanti, PC Africa, M Fedele, C Vergara… - Computer Methods in …, 2021 - Elsevier
Since myocardial fibers drive the electric signal propagation throughout the myocardium,
accurately modeling their arrangement is essential for simulating heart electrophysiology …

[HTML][HTML] Computational modeling for cardiac resynchronization therapy

AWC Lee, CM Costa, M Strocchi, CA Rinaldi… - Journal of …, 2018 - Springer
Cardiac resynchronization therapy (CRT) is an effective treatment for heart failure (HF)
patients with an electrical substrate pathology causing ventricular dyssynchrony. However …

[HTML][HTML] Efficient computation of electrograms and ECGs in human whole heart simulations using a reaction-eikonal model

A Neic, FO Campos, AJ Prassl, SA Niederer… - Journal of computational …, 2017 - Elsevier
Anatomically accurate and biophysically detailed bidomain models of the human heart have
proven a powerful tool for gaining quantitative insight into the links between electrical …

Comparison of propagation models and forward calculation methods on cellular, tissue and organ scale atrial electrophysiology

C Nagel, CB Espinosa, K Gillette… - IEEE Transactions …, 2022 - ieeexplore.ieee.org
Objective: The bidomain model and the finite element method are an established standard
to mathematically describe cardiac electrophysiology, but are both suboptimal choices for …

[HTML][HTML] An automata-based cardiac electrophysiology simulator to assess arrhythmia inducibility

D Serra, P Romero, I Garcia-Fernandez, M Lozano… - Mathematics, 2022 - mdpi.com
Personalized cardiac electrophysiology simulations have demonstrated great potential to
study cardiac arrhythmias and help in therapy planning of radio-frequency ablation. Its …

[HTML][HTML] Ectopic beats arise from micro-reentries near infarct regions in simulations of a patient-specific heart model

RS Oliveira, S Alonso, FO Campos, BM Rocha… - Scientific reports, 2018 - nature.com
Ectopic beats are known to be involved in the initiation of a variety of cardiac arrhythmias.
Although their location may vary, ectopic excitations have been found to originate from …

Personalization of a cardiac electromechanical model using reduced order unscented Kalman filtering from regional volumes

S Marchesseau, H Delingette, M Sermesant… - Medical image …, 2013 - Elsevier
Patient-specific cardiac modeling can help in understanding pathophysiology and therapy
planning. However it requires to combine functional and anatomical data in order to build …

Deep computational model for the inference of ventricular activation properties

L Li, J Camps, A Banerjee, M Beetz… - … Workshop on Statistical …, 2022 - Springer
Patient-specific cardiac computational models are essential for the efficient realization of
precision medicine and in-silico clinical trials using digital twins. Cardiac digital twins can …

Understanding the mechanisms amenable to CRT response: from pre-operative multimodal image data to patient-specific computational models

C Tobon-Gomez, N Duchateau, R Sebastian… - Medical & biological …, 2013 - Springer
This manuscript describes our recent developments towards better understanding of the
mechanisms amenable to cardiac resynchronization therapy response. We report the results …

[HTML][HTML] Evaluation of a rapid anisotropic model for ECG simulation

S Pezzuto, P Kal'avský, M Potse, FW Prinzen… - Frontiers in …, 2017 - frontiersin.org
State-of-the-art cardiac electrophysiology models that are able to deliver physiologically
motivated activation maps and electrocardiograms (ECGs) can only be solved on high …