Lymphangioleiomyomatosis: pathogenesis, clinical features, diagnosis, and management

C McCarthy, N Gupta, SR Johnson, JY Jane… - The Lancet …, 2021 - thelancet.com
Lymphangioleiomyomatosis (LAM) is a slowly progressive, low-grade, metastasising
neoplasm of women, characterised by infiltration of the lung parenchyma with abnormal …

Lymphangioleiomyomatosis—a wolf in sheep's clothing

EP Henske, FX McCormack - The Journal of clinical …, 2012 - Am Soc Clin Investig
Lymphangioleiomyomatosis (LAM) is a rare progressive lung disease of women. LAM is
caused by mutations in the tuberous sclerosis genes, resulting in activation of the mTOR …

Uterine PEComas: a morphologic, immunohistochemical, and molecular analysis of 32 tumors

JA Bennett, AC Braga, A Pinto… - The American journal …, 2018 - journals.lww.com
Uterine perivascular epithelioid cell tumors (PEComas) are rare neoplasms that may show
overlapping morphology and immunohistochemistry with uterine smooth muscle tumors. In …

Diffuse cystic lung disease. Part I

N Gupta, R Vassallo… - American journal of …, 2015 - atsjournals.org
The diffuse cystic lung diseases (DCLDs) are a group of pathophysiologically heterogenous
processes that are characterized by the presence of multiple spherical or irregularly shaped …

Single-cell transcriptomic analysis identifies a unique pulmonary lymphangioleiomyomatosis cell

M Guo, JJ Yu, AK Perl… - American journal of …, 2020 - atsjournals.org
Rationale: Lymphangioleiomyomatosis (LAM) is a metastatic neoplasm of reproductive-age
women associated with mutations in tuberous sclerosis complex genes. LAM causes cystic …

Lymphangioleiomyomatosis: calling it what it is: a low-grade, destructive, metastasizing neoplasm

FX McCormack, WD Travis, TV Colby… - American journal of …, 2012 - atsjournals.org
Lymphangioleiomyomatosis (LAM) is a progressive cystic lung disease primarily affecting
women that has historically been classified and clinically managed as a nonneoplastic …

Lymphangioleiomyomatosis screening in women with tuberous sclerosis

CJ Cudzilo, RD Szczesniak, AS Brody, MS Rattan… - Chest, 2013 - Elsevier
Background Lymphangioleiomyomatosis (LAM) occurs in at least 40% of women with
tuberous sclerosis complex (TSC), as diagnosed based on chest CT scan findings. Early …

Lymphangioleiomyomatosis

SR Johnson - Orphan lung diseases: a clinical guide to rare lung …, 2023 - Springer
Lymphangioleiomyomatosis (LAM) is a rare multisystem disease which predominantly
affects women. The disease occurs both sporadically and is common in women with …

Clinical features, epidemiology, and therapy of lymphangioleiomyomatosis

AM Taveira-DaSilva, J Moss - Clinical epidemiology, 2015 - Taylor & Francis
Lymphangioleiomyomatosis (LAM) is a multisystem disease of women, characterized by
proliferation of abnormal smooth muscle-like LAM cells, leading to the formation of lung …

Perivascular epithelioid cell tumors (PEComa) of the gynecologic tract

JA Bennett, E Oliva - Genes, Chromosomes and Cancer, 2021 - Wiley Online Library
PEComas of the female genital tract are rare mesenchymal neoplasms that are most
common in the uterus, but also may occur in other gynecologic locations. As they …