Therapeutic synthetic and natural materials for immunoengineering
Immunoengineering is a rapidly evolving field that has been driving innovations in
manipulating immune system for new treatment tools and methods. The need for materials …
manipulating immune system for new treatment tools and methods. The need for materials …
Hi gh-throughput K inetics using capillary E lectrophoresis and R obotics (HiKER) platform used to study T7, T3, and Sp6 RNA polymerase misincorporation
T7 RNA Polymerase (RNAP) is a widely used enzyme with recent applications in the
production of RNA vaccines. For over 50 years denaturing sequencing gels have been used …
production of RNA vaccines. For over 50 years denaturing sequencing gels have been used …
IFIT1 is rapidly evolving and exhibits disparate antiviral activities across 11 mammalian orders
MB McDougal, AM De Maria, E Nakahara, IN Boys… - bioRxiv, 2024 - biorxiv.org
Mammalian mRNAs possess an N7-methylguanosine (m7G) cap and 2'O methylation of the
initiating nucleotide at their 5'end, whereas certain viral RNAs lack these characteristic …
initiating nucleotide at their 5'end, whereas certain viral RNAs lack these characteristic …
Co-transcriptional capping using an RNA capping enzyme-T7 RNA polymerase fusion protein
Abstract mRNA vaccines and therapeutics are highly effective and can be developed and
manufactured with a relatively short lead time. Here we report an all-enzyme platform to …
manufactured with a relatively short lead time. Here we report an all-enzyme platform to …
[HTML][HTML] A comparative exploration of mRNA capping enzymes
Y Wang, X Wang, W Li, X Chen, Y Lu - Biotechnology Notes, 2024 - Elsevier
With the wide application of messenger RNA (mRNA) technology in medicine and vaccine
fields, higher requirements are put forward for mRNA expression efficiency in vivo. Since the …
fields, higher requirements are put forward for mRNA expression efficiency in vivo. Since the …
eIF4E-Dependent Capture of the Monomeric HIV-1 RNA Genome
K Singh - 2024 - search.proquest.com
The human immunodeficiency virus type-1 (HIV-1) RNA genome's 5'-untranslated region (5'-
Leader, 5'-L) serves as a master regulator for numerous viral replication processes within a …
Leader, 5'-L) serves as a master regulator for numerous viral replication processes within a …
The Design, Construction, And Testing of Nucleic Acid Vaccines Against Salmonella Enterica Subspecies Enterica Serovar Javiana
AA Nguyen - 2024 - search.proquest.com
Salmonella spp. is a Gram-negative bacterium that has the ability to replicate within a variety
of hosts, or within the environment, including water, soil, and vegetation. These …
of hosts, or within the environment, including water, soil, and vegetation. These …
[HTML][HTML] 多様なエンジニアリング戦略によって広がる人工mRNA の可能性
大野博久， 齊藤博英 - Journal of Japanese Biochemical …, 2024 - seikagaku.jbsoc.or.jp
新型コロナウイルスワクチンの実用化により人工 mRNA が大きな注目を集めている.
設計が容易でゲノムに組み込まれる恐れがないなど, 多くの利点を持つ人工 mRNA は …
設計が容易でゲノムに組み込まれる恐れがないなど, 多くの利点を持つ人工 mRNA は …