Mechanisms contributing to prefrontal cortex maturation during adolescence

A Caballero, R Granberg, KY Tseng - Neuroscience & Biobehavioral …, 2016 - Elsevier
Adolescence is defined as a transitional period between childhood and adulthood
characterized by changes in social interaction and acquisition of mature cognitive abilities …

[HTML][HTML] The role of parvalbumin interneurons in neurotransmitter balance and neurological disease

L Nahar, BM Delacroix, HW Nam - Frontiers in psychiatry, 2021 - frontiersin.org
While great progress has been made in the understanding of neurological illnesses, the
pathologies, and etiologies that give rise to these diseases still remain an enigma, thus, also …

[HTML][HTML] Therapeutic deep brain stimulation in Parkinsonian rats directly influences motor cortex

Q Li, Y Ke, DCW Chan, ZM Qian, KKL Yung, H Ko… - Neuron, 2012 - cell.com
Much recent discussion about the origin of Parkinsonian symptoms has centered around the
idea that they arise with the increase of beta frequency waves in the EEG. This activity may …

The neonatal ventral hippocampal lesion as a heuristic neurodevelopmental model of schizophrenia

KY Tseng, RA Chambers, BK Lipska - Behavioural brain research, 2009 - Elsevier
Traditionally, animal models of schizophrenia were predominantly pharmacological
constructs focused on phenomena linked to dopamine and glutamate neurotransmitter …

Dopamine modulation of prefrontal cortical interneurons changes during adolescence

KY Tseng, P O'Donnell - Cerebral Cortex, 2007 - academic.oup.com
Adolescence is marked by profound psychological and neuroendocrine changes. Cognitive
functions that depend on the prefrontal cortex and dopamine (DA), such as decision making …

Smoking, nicotine and neuropsychiatric disorders

P Dome, J Lazary, MP Kalapos, Z Rihmer - Neuroscience & Biobehavioral …, 2010 - Elsevier
Tobacco smoking is an extremely addictive and harmful form of nicotine (NIC) consumption,
but unfortunately also the most prevalent. Although disproportionately high frequencies of …

[HTML][HTML] Area-specific reestablishment of damaged circuits in the adult cerebral cortex by cortical neurons derived from mouse embryonic stem cells

KA Michelsen, S Acosta-Verdugo, M Benoit-Marand… - Neuron, 2015 - cell.com
Pluripotent stem-cell-derived neurons constitute an attractive source for replacement
therapies, but their utility remains unclear for cortical diseases. Here, we show that neurons …

Neurotransmitters and prefrontal cortex–limbic system interactions: implications for plasticity and psychiatric disorders

AD Arco, F Mora - Journal of neural transmission, 2009 - Springer
The prefrontal cortex (PFC) efferent projections to limbic areas facilitate a top-down control
on the execution of goal-directed behaviours. The PFC sends glutamatergic outputs to limbic …

Dopaminergic regulation of inhibitory and excitatory transmission in the basolateral amygdala–prefrontal cortical pathway

SB Floresco, TT Maric - Journal of Neuroscience, 2007 - Soc Neuroscience
Projections from the basolateral amygdala (BLA) and dopamine (DA) input from the ventral
tegmental area (VTA) converge in the medial prefrontal cortex (mPFC), forming a neural …

[HTML][HTML] The role of dopamine and endocannabinoid systems in prefrontal cortex development: Adolescence as a critical period

KZ Peters, F Naneix - Frontiers in Neural Circuits, 2022 - frontiersin.org
The prefrontal cortex plays a central role in the control of complex cognitive processes
including action control and decision making. It also shows a specific pattern of delayed …