Nanomaterials exhibit structural and functional heterogeneity among individual
nanoparticles, thus requiring a capability to study single nanoparticles. While electron …

The ability to monitor biomolecular reactions in a real-time and label free manner is nearly
synonymous with the surface plasmon resonance (SPR) technique. At its basis, SPR relies …

Exosome analysis is a promising tool for clinical and biological research applications.
However, detection and biomarker quantification of exosomes is technically challenging …

Electrochemical (EC) impacts of single nanoparticles (NPs) on an ultramicroelectrode are
coupled with optics to identify chemical processes at the level of individual NPs. While the …

Recent high-bandwidth recordings of the oxidation and dissolution of 35 nm radius Ag
nanoparticles at a Au microelectrode show that these nanoparticles undergo multiple …

Abstract Development of nanotechnology and corresponding industries during the last
decade resulted in a new challenge for analytical science. This includes an ultrasensitive …

Conspectus Interest in nanoparticles has vigorously increased over the last 20 years as
more and more studies show how their use can potentially revolutionize science and …

Specialized applications of nanoparticles often call for particular, well-characterized particle
size distributions in solution, but this property can prove difficult to measure. High-throughput …

Optical modeling coupled to experiments show that a microscope operating in reflection
mode allows imaging, through solutions or even a microfluidic cover, various kinds of …

Interferometric scattering microscopy (iSCAT) has rapidly developed as a quantitative tool
for the label-free detection of single macromolecules and nanoparticles. In practice, this …