Medical comorbidities are more common in children with autism spectrum disorders (ASD)
than in the general population. Some genetic disorders are more common in children with …

Down syndrome (DS) is one of the most well-recognized genetic disorders. Persons with DS
are known to have a variety of co-morbid medical problems, affecting nearly all organ …

Over the past century, the life expectancy of people born with Down syndrome has
increased from 9 to 60 years, 1 with data indicating that it could match the general …

This clinical report is designed to assist the pediatrician in caring for the child, adolescent,
and family in whom a diagnosis of Down syndrome has been confirmed by chromosome …

Down syndrome (DS) is the most common genetic disorder in live-born infants. Children with
DS are at increased risk of numerous endocrinal comorbidities. The information contained in …

Purpose/Objective: Although the concept of quality of life (QoL) has become a reference
framework for the provision of support and services to people with intellectual disability (ID) …

Clinical observations and preclinical studies both suggest that Down syndrome (DS) may be
associated with significant metabolic and bioenergetic alterations. However, the relevant …

Down syndrome is the most common chromosomal abnormality diagnosed in newborn
babies. Infants with Down syndrome have characteristic dysmorphic features and can have …

Patients with Down syndrome (DS) are at risk of multiorgan dysfunction; kidney and
urological impairment are common. This is due to a likely increased risk of congenital kidney …

Simple Summary Patients with Down Syndrome have been thoroughly studied over the past
100 years, and many attempts have been made to attain insight into the developmental …