Congenital Diaphragmatic hernia (CDH) is a condition characterized by a defect in the
diaphragm leading to protrusion of abdominal contents into the thoracic cavity interfering …

The transition from a fetus to a newborn is the most complex physiologic adaptation that
occurs in human experience. Before medicalization of delivery, the transition had to occur …

Pathophysiology and Management of Persistent Pulmonary Hypertension of the Newborn -
Clinics in Perinatology Skip to Main Content Advertisement Clinics in Perinatology Log in …

Persistent pulmonary hypertension of the newborn (PPHN) is a syndrome of failed
circulatory adaptation at birth, seen in about 2/1000 live born infants. While it is mostly seen …

Prostacyclin (PGI 2) is a member of the prostanoid group of eicosanoids that regulate
homeostasis, hemostasis, smooth muscle function and inflammation. Prostanoids are …

Pulmonary hypertension (PH) is a common complication of neonatal respiratory diseases,
including bronchopulmonary dysplasia (BPD), and recent studies have increased …

Persistent pulmonary hypertension of the newborn (PPHN) is a significant clinical problem
characterized by refractory and severe hypoxemia secondary to elevated pulmonary …

Persistent pulmonary hypertension of the newborn (PPHN) is one of the main causes of
neonatal morbidity and mortality. It is characterized by sustained elevation of pulmonary …

Inhaled nitric oxide (iNO) is approved for use in persistent pulmonary hypertension of the
newborn (PPHN) but does not lead to sustained improvement in oxygenation in one-third of …

Failure of the normal circulatory adaptation to extrauterine life results in persistent
pulmonary hypertension of the newborn (PPHN). Although this condition is most often …