The certainty of a few good reactions

AD Moorhouse, JA Homer, JE Moses - Chem, 2023 - cell.com
The impact of click chemistry was recently recognized with the 2022 Nobel Prize in
Chemistry. The breadth of areas where click chemistry has accelerated discovery is …

Rapid Generation of P (V)–F Bonds Through the Use of Sulfone Iminium Fluoride Reagents

LP Miller, JA Vogel, S Harel, JM Krussman… - Organic …, 2023 - ACS Publications
Phosphorus–fluorine bonds have become increasingly relevant in the pharmaceutical
industry. To continue their exploration, more efficient synthetic methods are needed. Here …

(2S)-2-(Difluoro (methoxy) methyl) pyrrolidine-1-sulfinyl fluoride as a new reagent in the Cl/F exchange reactions with aryl and alkyl sulfonyl chlorides

SV Zasukha, AB Rozhenko… - Journal of Fluorine …, 2024 - Elsevier
Abstract The reaction of (2S)-2-(difluoro (methoxy) methyl) pyrrolidine-1-sulfinyl fluoride with
aryl, heteryl and alkyl sulfonyl chlorides provides a convenient synthetic route to sulfonyl …