Laboratory testing for prescription opioids

MC Milone - Journal of medical toxicology, 2012 - Springer
Opioid analgesic misuse has risen significantly over the past two decades, and these drugs
now represent the most commonly abused class of prescription medications. They are a …

Assisted suicide by fentanyl intoxication due to excessive transdermal application

M Juebner, M Fietzke, J Beike, MA Rothschild… - International journal of …, 2014 - Springer
Herein, we report a case of an assisted suicide committed by application of 34 matrix-based
fentanyl-containing transdermal therapeutic systems (TTS) with different release rates. The …

A comprehensive LC‐MS‐based quantitative analysis of fentanyl‐like drugs in plasma and urine

S Cooreman, C Deprez, F Martens… - Journal of separation …, 2010 - Wiley Online Library
Abstract Fentanyl, norfentanyl, alfentanil, sufentanil, remifentanil and 3‐methylfentanyl are
potent, short‐acting, synthetic narcotic analgesics that are not revealed in standard opiate …

Quantitative low-volume assay for simultaneous determination of fentanyl, norfentanyl, and minor metabolites in human plasma and urine by liquid chromatography …

NS Mahlke, V Ziesenitz, G Mikus, G Skopp - International journal of legal …, 2014 - Springer
A rapid and sensitive liquid chromatography/tandem mass spectrometric (LC-MS/MS)
method for simultaneous quantification of fentanyl (F), norfentanyl (NF) …

Paper spray mass spectrometry utilized with a synthetic microporous polyolefin silica matrix substrate in the rapid detection and identification of more than 190 …

I W. De Silva, AN Couch… - Journal of the American …, 2020 - ACS Publications
Fentanyl and its related synthetic analogs have recently become more readily available as a
growing threat to public safety, such as pain relief and anesthetics. Sources of fentanyl are …

Development and validation of a sensitive ultra performance liquid chromatography tandem mass spectrometry method for the analysis of fentanyl and its major …

R Verplaetse, J Tytgat - Journal of Chromatography B, 2010 - Elsevier
Fentanyl and its major metabolite norfentanyl often occur in low doses in biological samples.
Therefore, a highly sensitive liquid chromatography tandem mass spectrometry (LC–MS/MS) …

Identification of fentanyl derivatives at trace levels with nonaqueous capillary electrophoresis‐electrospray‐tandem mass spectrometry (MSn, n = 2, 3): Analytical …

J Rittgen, M Pütz, R Zimmermann - Electrophoresis, 2012 - Wiley Online Library
The identification of fentanyl derivatives at trace levels employing capillary electrophoresis
coupled to electrospray ionization tandem mass spectrometry (CE‐ESI‐MS n, n= 2, 3) is …

Bupivacaine metabolite can interfere with norfentanyl measurement by LC–MS/MS

G Mahowald, T Khaliq, S Basu, D Griggs… - The Journal of …, 2022 - academic.oup.com
Background Liquid chromatography coupled to tandem mass spectrometry (LC–MS/MS) is
the gold standard for the measurement of fentanyl and norfentanyl (NF) in urine and is …

[HTML][HTML] Application of a rapid ESI-MS/MS method for quantitative analysis of docetaxel in polymeric matrices of PLGA and PLGA-PEG nanoparticles through direct …

P Rafiei, D Michel, A Haddadi - American Journal of Analytical …, 2015 - scirp.org
Docetaxel is a member of taxan family of antineoplastic agents widely used in cancer
chemotherapy. However, application of conventional chemotherapy with commercial …

Multianalyte determination versus one-at-a-time methodologies

M De la Guardia, S Armenta - Comprehensive Analytical Chemistry, 2011 - Elsevier
In today's modern society the tremendous demand for analytical information has created a
growing need of techniques capable of measure and quantify a large variety of different …