Glycoproteomics: growing up fast

DR Thomas, NE Scott - Current opinion in structural biology, 2021 - Elsevier
Highlights•Approaches for glycoproteomics are rapidly diversifying expanding the classes of
glycosylation able to be studied en masse.•N-linked, Mucin-O-linked and O-GlcNAc …

Structural basis of mammalian mucin processing by the human gut O-glycopeptidase OgpA from Akkermansia muciniphila

B Trastoy, A Naegeli, I Anso, J Sjögren… - Nature …, 2020 - nature.com
Akkermansia muciniphila is a mucin-degrading bacterium commonly found in the human gut
that promotes a beneficial effect on health, likely based on the regulation of mucus thickness …

Analysis of the healthy platelet proteome identifies a new form of domain-specific O-fucosylation

CB Houlahan, Y Kong, B Johnston, M Cielesh… - Molecular & Cellular …, 2024 - ASBMB
Platelet activation induces the secretion of proteins that promote platelet aggregation and
inflammation. However, detailed analysis of the released platelet proteome is hampered by …

Site-specific N-and O-glycosylation analysis of human plasma fibronectin

D Liu, S Wang, J Zhang, W Xiao, CH Miao… - Frontiers in …, 2021 - frontiersin.org
Human plasma fibronectin is an adhesive protein that plays a crucial role in wound healing.
Many studies had indicated that glycans might mediate the expression and functions of …

Total retention liquid chromatography–mass spectrometry to achieve maximum protein sequence coverage

ME Jennings, JR Silveira, KM Treier, PB Tracy… - Analytical …, 2021 - ACS Publications
Peptide identification by liquid chromatography–mass spectrometry (LC–MS) requires
retention and elution of peptides from the LC column. Although medium and hydrophobic …

Multichannel Recovery Potential with Activated Autologous Intraovarian Platelet-Rich Plasma and Its Derivatives

ES Sills, SH Wood - Medicines, 2023 - mdpi.com
Platelet-rich plasma (PRP) is an 'orthobiologic'with recognized roles in plastic surgery,
musculoskeletal disorders, dentistry, dermatology, and more recently,'ovarian rejuvenation' …

Total cell N-glycosylation is altered during neuronal differentiation of iPSC to NSC and is disturbed by trisomy 21

A Cindrić, F Vučković, A Murray, T Klarić, I Alić… - bioRxiv, 2023 - biorxiv.org
Down syndrome (DS) is a genetic condition caused by trisomy 21 (T21) and characterized
by a range of neurological symptoms including intellectual disability, early onset of …

Polypeptide-GalNAc-Transferase-13 shows prognostic impact in breast cancer

E Fernandez, L Ubillos, N Elgul, MF Festari, D Mazal… - Cancers, 2021 - mdpi.com
Simple Summary The knowledge of the molecular mechanisms underlying breast
tumorigenesis has allowed the identification of an increasing number of biomarkers, which …

[PDF][PDF] Polypeptide-GalNAc-Transferase-13 Shows Prognostic Impact in Breast Cancer. Cancers 2021, 13, 5616

E Fernandez, L Ubillos, N Elgul, MF Festari, D Mazal… - 2021 - academia.edu
Breast cancer is a public health concern and is currently the fifth cause of mortality
worldwide. Identification of different biological subtypes is essential for clinical management; …

[PDF][PDF] セマンティックウェーブ技術を活用した糖鎖関連経路情報のバイオインフォマティクスリソースの開発

李宣明 - soka.repo.nii.ac.jp
A lot of databases have been developed with a huge amount of glycomics data to help us
understand the function and impact of glycans on cellular activity. On the other hand, many …