The net reclassification improvement (NRI) is an increasingly popular measure for
evaluating improvements in risk predictions. This article details a review of 67 publications in …

The TRIPOD (Transparent Reporting of a multivariable prediction model for Individual
Prognosis Or Diagnosis) Statement includes a 22-item checklist, which aims to improve the …

Globally, lung cancer is the leading cause of cancer death and is a major public health
problem. Because lung cancer is usually diagnosed at an advanced stage, survival is …

Abstract The Rotterdam Study is a prospective cohort study ongoing since 1990 in the city of
Rotterdam in The Netherlands. The study targets cardiovascular, endocrine, hepatic …

Developed from the authors' graduate-level biostatistics course, Applied Categorical and
Count Data Analysis, Second Edition explains how to perform the statistical analysis of …

Home and 24-hour blood pressure (BPHome and BP24h) are believed to improve the
prognostic value of office BP (BPOffice) alone, but the evidence has limitations such as that …

The incidence of type 2 diabetes can be reduced substantially by implementing preventive
measures in high-risk individuals, but this requires prior knowledge of disease risk in the …

Background We investigate whether the urinary proteome refines the diagnosis of renal
dysfunction, which affects over 10% of the adult population. Methods We measured serum …

Aims Several published diabetes prediction models include information about family history
of diabetes. The aim of this study was to extend the previously developed German Diabetes …

Purpose This review discusses the utility of risk scores, specifically, the role of preoperative
risk scores in guiding the management of surgical patients, approaches to evaluate the …