Artificial Intelligence Methods and Models for Retro-Biosynthesis: A Scoping Review

G Gricourt, P Meyer, T Duigou, JL Faulon - ACS Synthetic Biology, 2024 - ACS Publications
Retrosynthesis aims to efficiently plan the synthesis of desirable chemicals by strategically
breaking down molecules into readily available building block compounds. Having a long …

[HTML][HTML] Enhancing Antimicrobial Resistance Strategies: Leveraging Artificial Intelligence for Improved Outcomes

AM Mohammed, M Mohammed, JK Oleiwi… - South African Journal of …, 2024 - Elsevier
Antimicrobial resistance (AMR) poses a formidable challenge to global health, threatening to
undermine the efficacy of antibiotics and jeopardize medical advances. Despite concerted …

AutoTemplate: enhancing chemical reaction datasets for machine learning applications in organic chemistry

LY Chen, YP Li - Journal of Cheminformatics, 2024 - Springer
This paper presents AutoTemplate, an innovative data preprocessing protocol, addressing
the crucial need for high-quality chemical reaction datasets in the realm of machine learning …

A critical methodological revisit on group-contribution based property prediction of ionic liquids with machine learning

P Cao, J Chen, G Chen, Z Qi, Z Song - Chemical Engineering Science, 2024 - Elsevier
As group-contribution (GC) concept is convenient and pragmatic for predictive property
modeling, exploring the limits of GC-based models by pairing different machine learning …

[HTML][HTML] Machine learning-assisted retrosynthesis planning: current status and future prospects

Y Wei, L Shan, T Qiu, D Lu, Z Liu - Chinese Journal of Chemical …, 2024 - Elsevier
Abstract Machine learning-assisted retrosynthesis planning aims to utilize machine learning
(ML) algorithms to find synthetic pathways for target compounds. In recent years, with the …

De novo drug design through gradient-based regularized search in information-theoretically controlled latent space

H Jang, S Seo, S Park, BJ Kim, GW Choi, J Choi… - Journal of Computer …, 2024 - Springer
Over the last decade, automatic chemical design frameworks for discovering molecules with
drug-like properties have significantly progressed. Among them, the variational autoencoder …

Chemoenzymatic synthesis planning by evaluating the synthetic potential in biocatalysis and chemocatalysis

X Liu, H Li, H Zhao - 2024 - chemrxiv.org
Chemoenzymatic synthesis integrates the advantages of chemocatalysis and biocatalysis to
design efficient synthesis routes. However, current computer-assisted chemoenzymatic …

Chemical Process Design Approaches Leveraging Process Modularization, Intensification, and Large Language Models

CB Mukta - 2024 - etd.auburn.edu
This dissertation investigates critical aspects of chemical engineering, including reactor
intensification, process expansion, distributed natural gas desulfurization, and large …