Although death is inevitable, individuals have long sought to alter the course of the ageing
process. Indeed, ageing has proved to be modifiable; by intervening in biological systems …

Wnt/β-catenin signaling, a highly conserved pathway through evolution, regulates key
cellular functions including proliferation, differentiation, migration, genetic stability …

Inflammation is emerging as one of the hallmarks of cancer, yet its role in most tumors
remains unclear. Whereas a minority of solid tumors are associated with overt inflammation …

Aspirin (acetylsalicylic acid) has become one of the most commonly used drugs, given its
role as an analgesic, antipyretic and agent for cardiovascular prophylaxis. Several decades …

Salicylates from plant sources have been used for centuries by different cultures to treat a
variety of ailments such as inflammation, fever and pain. A chemical derivative of salicylic …

Metastatic colorectal cancer is a prevalent disease for which novel targeted therapies and
biologically based combinations are under development. Cytotoxic chemotherapy doublets …

Emerging scientific evidence indicates that inflammation is a critical component of tumor
promotion and progression. Most cancers originate from sites of chronic irritation, infections …

Plants, like other multicellular organisms, survive through a delicate balance between
growth and defense against pathogens. Salicylic acid (SA) is a major defense signal in …

Epidemiological studies suggest that olive oil intake is associated to a reduced risk of
cancer. Recently, the chemopreventive activity of olive oil has been attributed to its unique …

Since colorectal cancer is one of the world's most common cancers, studies on its prevention
and early diagnosis are an emerging area of clinical oncology these days. For this study, a …