Progress and challenge for computational quantification of tissue immune cells
Tissue immune cells have long been recognized as important regulators for the
maintenance of balance in the body system. Quantification of the abundance of different …
maintenance of balance in the body system. Quantification of the abundance of different …
[HTML][HTML] Dysregulation of the immune environment in the airways during HIV infection
HIV-1 increases susceptibility to pulmonary infection and disease, suggesting pathogenesis
in the lung. However, the lung immune environment during HIV infection remains poorly …
in the lung. However, the lung immune environment during HIV infection remains poorly …
[HTML][HTML] A Pilot Cross-Sectional Study of Immunological and Microbiome Profiling Reveals Distinct Inflammatory Profiles for Smokers, Electronic Cigarette Users, and …
PG Shields, KL Ying, TM Brasky, JL Freudenheim, Z Li… - Microorganisms, 2023 - mdpi.com
Smokers (SM) have increased lung immune cell counts and inflammatory gene expression
compared to electronic cigarette (EC) users and never-smokers (NS). The objective of this …
compared to electronic cigarette (EC) users and never-smokers (NS). The objective of this …
Uncovering the Bronchoalveolar Single-Cell Landscape of Patients With Pulmonary Tuberculosis With Human Immunodeficiency Virus Type 1 Coinfection
G Xiao, W Huang, Y Zhong, M Ou, T Ye… - The Journal of …, 2024 - academic.oup.com
Background Coinfection of human immunodeficiency virus type 1 (HIV-1) is the most
significant risk factor for tuberculosis (TB). The immune responses of the lung are essential …
significant risk factor for tuberculosis (TB). The immune responses of the lung are essential …
Investigating the Potential Shared Molecular Mechanisms between COVID-19 and Alzheimer's Disease via Transcriptomic Analysis
Y Fan, X Liu, F Guan, X Hang, X He, J Jin - Viruses, 2024 - mdpi.com
SARS-CoV-2 caused the COVID-19 pandemic. COVID-19 may elevate the risk of cognitive
impairment and even cause dementia in infected individuals; it may accelerate cognitive …
impairment and even cause dementia in infected individuals; it may accelerate cognitive …
[HTML][HTML] Higher neutrophil-lymphocyte ratio in TB/HIV co-infection compared to pulmonary tuberculosis
N Sulastri, B Alisjahbana, R Livia… - The Indonesian …, 2021 - inabj.org
BACKGROUND: Neutrophils and lymphocytes play a significant role in inflammation and a
high ratio of neutrophils over lymphocytes (NLR) has been used as an inflammatory marker …
high ratio of neutrophils over lymphocytes (NLR) has been used as an inflammatory marker …
[HTML][HTML] Complex interactions between human immunodeficiency virus type-1, sex, and osteopontin influence viral replication and leukocyte proportions in tissues
FJ Mahmud, E Greif, T Boucher, KA Metcalf Pate… - Frontiers in …, 2021 - frontiersin.org
Evidence suggesting that HIV pathogenesis differs by sex, a variable known to influence the
extent and breadth of immune responses in health and disease continues to accumulate …
extent and breadth of immune responses in health and disease continues to accumulate …
[HTML][HTML] Transcription factor ZNF683 inhibits SIV/HIV replication through regulating IFNγ secretion of CD8+ T cells
Y Lu, MX Zhang, W Pang, TZ Song, HY Zheng, RR Tian… - Viruses, 2022 - mdpi.com
Pulmonary microbial invasion frequently occurs during AIDS progression in HIV patients.
Inflammatory cytokines and other immunoregulatory factors play important roles in this …
Inflammatory cytokines and other immunoregulatory factors play important roles in this …
[HTML][HTML] Discrepancy between Mtb-specific IFN-γ and IgG responses in HIV-positive people with low CD4 counts
Background Tuberculosis (TB) is a leading infectious cause of death worldwide and treating
latent TB infection (LTBI) with TB preventative therapy is a global priority. This study aimed to …
latent TB infection (LTBI) with TB preventative therapy is a global priority. This study aimed to …
Inflammatory profiles in sputum and blood of people with TB with and without HIV coinfection
Although tuberculosis (TB) remains a major killer among infectious diseases and the leading
cause of death for people with HIV, drivers of immunopathology, particularly at the site of …
cause of death for people with HIV, drivers of immunopathology, particularly at the site of …