This review focuses on the role of the peripheral nervous system in cutaneous biology and
disease. During the last few years, a modern concept of an interactive network between …

The interaction between components of the nervous system and multiple target cells in the
cutaneous immune system has been receiving increasing attention. It has been observed …

57 ABSTRACT A method of and composition for concentrating athera peutic agent in an
inflamed dermal region are disclosed. The composition, which is also used in the method, is …

Background: Substance P, an undecapeptide neurotransmitter, has been implicated in the
pathophysiology of psoriasis and pruritus. Objective: Safety and efficacy of topical capsaicin …

Background Although some patients with psoriasis vulgaris also complain of severe pruritus,
the data available regarding pruritus in psoriasis are sparse. Objectives To clarify the …

Stress alters murine hair growth, depending on substance P-mediated neurogenic
inflammation and nerve growth factor (NGF), a key modulator of hair growth termination …

Connections between nerve fibres and cutaneous cells have been studied using confocal
and electron microscopy. In the skin, nerve fibres may secrete neuromediators, ie substance …

Stress has long been discussed controversially as a cause of hair loss. However, solid proof
of stress‐induced hair growth inhibition had long been missing. If psychoemotional stress …

Keratinocytes, a key cellular component both for homeostasis and pathophysiologic
processes of the skin, secrete a number of cytokines and are stimulated by several growth …

The pathogenesis of psoriasis is incompletely understood but cutaneous neurogenic
inflammation is probably involved. This involvement is suggested by a number of clinical …