Humans exhibit considerable variability in their immune responses to the same immune
challenges. Such variation is widespread and affects individual and population‐level …

Human genetics has emerged as one of the most dynamic areas of biology, with a
broadening societal impact. In this review, we discuss recent achievements, ongoing efforts …

Infections have imposed strong selection pressures throughout human evolution, making the
study of natural selection's effects on immunity genes highly complementary to disease …

Influenza A virus (IAV) infections are frequent every year and result in a range of disease
severity. Here, we wanted to explore the potential contribution of transposable elements …

Genetic variants, including mobile element insertions (MEIs), are known to impact the
epigenome. We hypothesized that genome graphs, which encapsulate genetic diversity …

Motivation Human epigenomic data has been generated by large consortia for thousands of
cell types to be used as a reference map of normal and disease chromatin states. Since …

Previously, we showed that a massively parallel reporter assay, mSTARR-seq, could be
used to simultaneously test for both enhancer-like activity and DNA methylation-dependent …

Only a third of immune-associated loci from genome-wide association studies (GWAS)
colocalize with expression quantitative trait loci (eQTLs). To learn about causal genes and …

Multi-ancestry statistical fine-mapping of cis-molecular quantitative trait loci (cis-molQTL)
aims to improve the precision of distinguishing causal cis-molQTLs from tagging variants …

Genome-wide association studies performed in patients with coronavirus disease 2019
(COVID-19) have uncovered various loci significantly associated with susceptibility to SARS …