Hormones and endocrine-disrupting chemicals: low-dose effects and nonmonotonic dose responses

LN Vandenberg, T Colborn, TB Hayes… - Endocrine …, 2012 - academic.oup.com
For decades, studies of endocrine-disrupting chemicals (EDCs) have challenged traditional
concepts in toxicology, in particular the dogma of “the dose makes the poison,” because …

[HTML][HTML] Endocrine-disrupting chemicals: review of toxicological mechanisms using molecular pathway analysis

O Yang, HL Kim, JI Weon, YR Seo - Journal of cancer prevention, 2015 - ncbi.nlm.nih.gov
Endocrine disruptors are known to cause harmful effects to human through various exposure
routes. These chemicals mainly appear to interfere with the endocrine or hormone systems …

Fetal origin of endocrine dysfunction in the adult: the phthalate model

DB Martinez-Arguelles, E Campioli, M Culty… - The Journal of steroid …, 2013 - Elsevier
Abstract Di-(2-ethylhexyl) phthalate (DEHP) is a plasticizer with endocrine disrupting
properties that is found ubiquitously in the environment as well as in human amniotic fluid …

Di-(2-ethylhexyl)-phthalate disrupts pituitary and testicular hormonal functions to reduce sperm quality in mature goldfish

M Golshan, A Hatef, M Socha, S Milla, IAE Butts… - Aquatic Toxicology, 2015 - Elsevier
Abstract Di-(2-ethylhexyl) phthalate (DEHP) interferes with male reproductive endocrine
system in mammals, however its effects on fish reproduction are largely unknown. We …

Medications as a potential source of exposure to phthalates among women of childbearing age

S Hernández-Díaz, YC Su, AA Mitchell, KE Kelley… - Reproductive …, 2013 - Elsevier
OBJECTIVE: To evaluate the association between the use of medications potentially
containing phthalates and urinary concentrations of specific phthalate metabolites around …

Production of phthalate esters by nuisance freshwater algae and cyanobacteria

B Babu, JT Wu - Science of the total environment, 2010 - Elsevier
Phthalate esters are widely distributed pollutants which originate from synthetic plasticizer
and are known to act as toxicants as well as environmental pheromones in the aquatic …

Male rat exposure to low dose of di (2-ethylhexyl) phthalate during pre-pubertal, pubertal and post-pubertal periods: Impact on sperm count, gonad histology and …

M Oudir, H Chader, B Bouzid, K Bendisari… - Reproductive …, 2018 - Elsevier
Abstract Di (2-ethylhexyl) phthalate (DEHP) is the most ubiquitous endocrine disruptor in the
environment. The present study aimed to investigate the low dose effects of DEHP on the …

Prenatal exposure to DEHP affects spermatogenesis and sperm DNA methylation in a strain-dependent manner

J Prados, L Stenz, E Somm, C Stouder, A Dayer… - PloS one, 2015 - journals.plos.org
Di-(2-ethylhexyl) phtalate (DEHP) is a plasticizer with endocrine disrupting properties found
ubiquitously in the environment and altering reproduction in rodents. Here we investigated …

Reproductive toxicity of di (2-ethylhexyl) phthalate in selenium-supplemented and selenium-deficient rats

P Erkekoglu, ND Zeybek, B Giray, E Asan… - Drug and Chemical …, 2011 - Taylor & Francis
Phthalates are abundantly produced plasticizers, and di (ethylhexyl) phthalate (DEHP) is the
most widely used derivative in various consumer products and medical devices. Animal …

The effects on steroidogenesis and histopathology of adult male Japanese quails (Coturnix coturnix japonica) testis following pre-pubertal exposure to di (n-butyl) …

UM Bello, MC Madekurozwa, HB Groenewald… - … and Physiology Part C …, 2014 - Elsevier
In the present study, we have investigated the effects of 30-day dietary (pre-pubertal)
exposure to different doses (0 (control), 1, 10, 50, 200 and 400 mg/kg bodyweight/day) of di …