Intracranial atherosclerotic stenosis: risk factors, diagnosis, and treatment
Intracranial atherosclerotic stenosis (ICAS) is one of the most frequent causes of stroke
worldwide and confers one of the greatest risks of recurrent stroke compared with other …
worldwide and confers one of the greatest risks of recurrent stroke compared with other …
Stroke in China: advances and challenges in epidemiology, prevention, and management
With over 2 million new cases annually, stroke is associated with the highest disability-
adjusted life-years lost of any disease in China. The burden is expected to increase further …
adjusted life-years lost of any disease in China. The burden is expected to increase further …
[HTML][HTML] Trial of endovascular therapy for acute ischemic stroke with large infarct
X Huo, G Ma, X Tong, X Zhang, Y Pan… - … England Journal of …, 2023 - Mass Medical Soc
Background The role of endovascular therapy for acute stroke with a large infarction has not
been extensively studied in differing populations. Methods We conducted a multicenter …
been extensively studied in differing populations. Methods We conducted a multicenter …
Effect of stenting plus medical therapy vs medical therapy alone on risk of stroke and death in patients with symptomatic intracranial stenosis: the CASSISS …
P Gao, T Wang, D Wang, DS Liebeskind, H Shi, T Li… - Jama, 2022 - jamanetwork.com
Importance Prior randomized trials have generally shown harm or no benefit of stenting
added to medical therapy for patients with symptomatic severe intracranial atherosclerotic …
added to medical therapy for patients with symptomatic severe intracranial atherosclerotic …
Reteplase versus Alteplase for Acute ischemic stroke
S Li, HQ Gu, H Li, X Wang, A Jin, S Guo… - … England Journal of …, 2024 - Mass Medical Soc
Background Alteplase is the standard agent used in early reperfusion therapy, but
alternative thrombolytic agents are needed. The efficacy and safety of reteplase as …
alternative thrombolytic agents are needed. The efficacy and safety of reteplase as …
Extracranial-intracranial bypass and risk of stroke and death in patients with symptomatic artery occlusion: the CMOSS randomized clinical trial
Y Ma, T Wang, H Wang, S Amin-Hanjani, X Tong… - Jama, 2023 - jamanetwork.com
Importance Prior trials of extracranial-intracranial (EC-IC) bypass surgery showed no benefit
for stroke prevention in patients with atherosclerotic occlusion of the internal carotid artery …
for stroke prevention in patients with atherosclerotic occlusion of the internal carotid artery …
Comparison of drug-eluting stent with bare-metal stent in patients with symptomatic high-grade intracranial atherosclerotic stenosis: a randomized clinical trial
B Jia, X Zhang, N Ma, D Mo, F Gao, X Sun… - JAMA …, 2022 - jamanetwork.com
Importance In-stent restenosis (ISR) is the primary reason for stroke recurrence after
intracranial stenting in patients who were treated with a standard bare-metal stent (BMS) …
intracranial stenting in patients who were treated with a standard bare-metal stent (BMS) …
Large vessel occlusion stroke due to intracranial atherosclerotic disease: identification, medical and interventional treatment, and outcomes
A De Havenon, OO Zaidat, S Amin-Hanjani… - Stroke, 2023 - Am Heart Assoc
Large vessel occlusion stroke due to underlying intracranial atherosclerotic disease (ICAD-
LVO) is prevalent in 10 to 30% of LVOs depending on patient factors such as vascular risk …
LVO) is prevalent in 10 to 30% of LVOs depending on patient factors such as vascular risk …
Remote ischaemic conditioning—a new paradigm of self-protection in the brain
DC Hess, RA Blauenfeldt, G Andersen… - Nature Reviews …, 2015 - nature.com
Remote ischaemic conditioning (RIC) triggers endogenous protective pathways in distant
organs such as the kidney, heart and brain, and represents an exciting new paradigm in …
organs such as the kidney, heart and brain, and represents an exciting new paradigm in …
Dual antiplatelet therapy in stroke and ICAS: subgroup analysis of CHANCE
Objective: We aimed to investigate whether the efficacy and safety of clopidogrel plus aspirin
vs aspirin alone were consistent between patients with and without intracranial arterial …
vs aspirin alone were consistent between patients with and without intracranial arterial …