▪ Abstract The genomes from three mammals (human, mouse, and rat), two worms, and
several yeasts have been sequenced, and more genomes will be completed in the near …

DNA sequences that regulate expression of the insulin gene are located within a region
spanning∼ 400 bp that flank the transcription start site. This region, the insulin promoter …

Lineage-ambiguous leukemias are high-risk malignancies of poorly understood genetic
basis. Here, we describe a distinct subgroup of acute leukemia with expression of myeloid, T …

We have conducted a comprehensive search for conserved elements in vertebrate
genomes, using genome-wide multiple alignments of five vertebrate species (human …

Accessing and analyzing the exponentially expanding genomic sequence and functional
data pose a challenge for biomedical researchers. Here we describe an interactive system …

The zebra finch is an important model organism in several fields, with unique relevance to
human neuroscience,. Like other songbirds, the zebra finch communicates through learned …

Mutations in distant regulatory elements can have a negative impact on human development
and health, yet because of the difficulty of detecting these critical sequences, we …

• Premise of study: To reliably identify lineages below the species level such as subspecies
or varieties, we propose an extension to DNA‐barcoding using next‐generation sequencing …

With an increasing number of vertebrate genomes being sequenced in draft or finished form,
unique opportunities for decoding the language of DNA sequence through comparative …

Disruption of signaling pathways such as those mediated by sonic hedgehog (Shh) or
platelet-derived growth factor (Pdgf) causes craniofacial abnormalities, including cleft palate …