[HTML][HTML] Reprogramming of glucose metabolism: the hallmark of malignant transformation and target for advanced diagnostics and treatments
Q Tang, S Wu, B Zhao, Z Li, Q Zhou, Y Yu… - Biomedicine & …, 2024 - Elsevier
Reprogramming of cancer metabolism has become increasingly concerned over the last
decade, particularly the reprogramming of glucose metabolism, also known as the" Warburg …
decade, particularly the reprogramming of glucose metabolism, also known as the" Warburg …
Role of cell division cycle-associated proteins in regulating cell cycle and promoting tumor progression
Z Wang, M Ren, W Liu, J Wu, P Tang - Biochimica et Biophysica Acta (BBA) …, 2024 - Elsevier
The cell division cycle-associated protein (CDCA) family is important in regulating cell
division. High CDCA expression is significantly linked to tumor development. This review …
division. High CDCA expression is significantly linked to tumor development. This review …
Multi-omic approaches to breast cancer metabolic phenotyping: Applications in diagnosis, prognosis, and the development of novel treatments
N Gómez-Cebrián, I Domingo-Ortí, JL Poveda… - Cancers, 2021 - mdpi.com
Simple Summary Breast cancer (BC) is a heterogeneous tumor type and has become the
leading cause of cancer worldwide, with 685,000 deaths forecast in 2020. The clinical …
leading cause of cancer worldwide, with 685,000 deaths forecast in 2020. The clinical …
Comprehensive analysis of the expression and prognosis value of chromobox family members in clear cell renal cell carcinoma
Y Zhu, Z Pu, Z Li, Y Lin, N Li, F Peng - Frontiers in oncology, 2021 - frontiersin.org
Clear cell renal cell carcinoma (ccRCC) accounts for 80% of all renal cancers and has a
poor prognosis. Chromobox (CBX) family protein expression has been reported in a variety …
poor prognosis. Chromobox (CBX) family protein expression has been reported in a variety …
Molecular mechanisms of multi-omic regulation in breast cancer
S Ochoa, E Hernández-Lemus - Frontiers in Oncology, 2023 - frontiersin.org
Breast cancer is a complex disease that is influenced by the concurrent influence of multiple
genetic and environmental factors. Recent advances in genomics and other high throughput …
genetic and environmental factors. Recent advances in genomics and other high throughput …
The epigenetic regulatory protein CBX2 promotes mTORC1 signalling and inhibits DREAM complex activity to drive breast cancer cell growth
LJ Bilton, C Warren, RM Humphries, S Kalsi, E Waters… - Cancers, 2022 - mdpi.com
Simple Summary Cancer develops due to the expression of genes that promote cell growth
and the repression of genes that limit growth. Epigenetics is a mechanism that regulates …
and the repression of genes that limit growth. Epigenetics is a mechanism that regulates …
Metabolic stratification of human breast tumors reveal subtypes of clinical and therapeutic relevance
Extensive metabolic heterogeneity in breast cancers has limited the deployment of
metabolic therapies. To enable patient stratification, we studied the metabolic landscape in …
metabolic therapies. To enable patient stratification, we studied the metabolic landscape in …
[HTML][HTML] Chromobox proteins in cancer: Multifaceted functions and strategies for modulation
J Wang, B Yang, X Zhang, S Liu… - International …, 2023 - spandidos-publications.com
Chromobox (CBX) proteins are important epigenetic regulatory proteins and are widely
involved in biological processes, such as embryonic development, the maintenance of stem …
involved in biological processes, such as embryonic development, the maintenance of stem …
CBX7 is dualistic in cancer progression based on its function and molecular interactions
J Li, T Ouyang, M Li, T Hong, MHS Alriashy… - Frontiers in …, 2021 - frontiersin.org
Chromobox protein homolog 7 (CBX7) is a member of the Chromobox protein family and
participates in the formation of the polycomb repressive complex 1 (PRC1). In cells, CBX7 …
participates in the formation of the polycomb repressive complex 1 (PRC1). In cells, CBX7 …
Subcellular expression pattern and clinical significance of CBX2 and CBX7 in breast cancer subtypes
S Park, J Choi, JK Song, B Jang, YH Maeng - Medical Molecular …, 2024 - Springer
Abstract Chromobox (CBX) 2 and CBX7, members of CBX family protein, show diverse
expression patterns and contrasting roles in certain cancers. We aimed to investigate the …
expression patterns and contrasting roles in certain cancers. We aimed to investigate the …