MicroRNAs as potential orchestrators of Alzheimer's disease-related pathologies: insights on current status and future possibilities
Alzheimer's disease (AD) is a progressive and deleterious neurodegenerative disease,
strongly affecting the cognitive functions and memory of seniors worldwide. Around 58% of …
strongly affecting the cognitive functions and memory of seniors worldwide. Around 58% of …
microRNAs as early biomarkers of Alzheimer's disease: A synaptic perspective
D Siedlecki-Wullich, AJ Miñano-Molina… - Cells, 2021 - mdpi.com
Pathogenic processes underlying Alzheimer's disease (AD) affect synaptic function from
initial asymptomatic stages, long time before the onset of cognitive decline and …
initial asymptomatic stages, long time before the onset of cognitive decline and …
Neuronal extracellular vesicles and associated microRNAs induce circuit connectivity downstream BDNF
A Antoniou, L Auderset, L Kaurani, E Sebastian… - Cell reports, 2023 - cell.com
Extracellular vesicles (EVs) have emerged as mediators of cellular communication, in part
via the delivery of associated microRNAs (miRNAs), small non-coding RNAs that regulate …
via the delivery of associated microRNAs (miRNAs), small non-coding RNAs that regulate …
MicroRNA-dependent control of neuroplasticity in affective disorders
HC Martins, G Schratt - Translational Psychiatry, 2021 - nature.com
Affective disorders are a group of neuropsychiatric disorders characterized by severe mood
dysregulations accompanied by sleep, eating, cognitive, and attention disturbances, as well …
dysregulations accompanied by sleep, eating, cognitive, and attention disturbances, as well …
Dendritic spine and synaptic plasticity in Alzheimer's disease: a focus on MicroRNA
EE Reza-Zaldivar, MA Hernández-Sápiens… - Frontiers in Cell and …, 2020 - frontiersin.org
Dendrites and dendritic spines are dynamic structures with pivotal roles in brain connectivity
and have been recognized as the locus of long-term synaptic plasticity related to cognitive …
and have been recognized as the locus of long-term synaptic plasticity related to cognitive …
MiR-218: a molecular switch and potential biomarker of susceptibility to stress
Low miR-218 expression in the medial prefrontal cortex (mPFC) is a consistent trait of
depression. Here we assessed whether miR-218 in the mPFC confers resilience or …
depression. Here we assessed whether miR-218 in the mPFC confers resilience or …
Development of in vitro 2D and 3D microelectrode arrays and their role in advancing biomedical research
The development of microelectrode arrays (MEAs) along with complementary advances in
electronics, mechanics and software to connect with these arrays has led to the in vitro …
electronics, mechanics and software to connect with these arrays has led to the in vitro …
MicroRNA regulation of prefrontal cortex development and psychiatric risk in adolescence
A Morgunova, C Flores - Seminars in cell & developmental biology, 2021 - Elsevier
In this review, we examine the role of microRNAs in the development of the prefrontal cortex
(PFC) in adolescence and in individual differences in vulnerability to mental illness. We …
(PFC) in adolescence and in individual differences in vulnerability to mental illness. We …
The molecular mechanism of baicalein repressing progression of gastric cancer mediating miR-7/FAK/AKT signaling pathway
D Qiao, J Xing, Y Duan, S Wang, G Yao, S Zhang, J Jin… - Phytomedicine, 2022 - Elsevier
Background Baicalein (BAI) has a significant anti-cancerous function in the treatment of
gastric cancer (GC). Focal adhesion kinase (FAK) is a key regulatory molecule in integrin …
gastric cancer (GC). Focal adhesion kinase (FAK) is a key regulatory molecule in integrin …
Neuroinflammation induces synaptic scaling through IL-1β-mediated activation of the transcriptional repressor REST/NRSF
F Buffolo, V Petrosino, M Albini, M Moschetta… - Cell death & …, 2021 - nature.com
Neuroinflammation is associated with synapse dysfunction and cognitive decline in patients
and animal models. One candidate for translating the inflammatory stress into structural and …
and animal models. One candidate for translating the inflammatory stress into structural and …