Whereas protease inhibitors have been developed successfully against hypertension and
viral infections, they have failed thus far as cancer drugs. With advances in cancer profiling …

Abstract Matrix metalloproteinase 9 (MMP-9/Gelatinase B) is overexpressed in pancreatic
ductal adenocarcinoma (PDAC) and plays a central role in tumor cell invasion and …

Objective and design The aim of this study was to determine whether different generations
(G) polyamidoamine (PAMAM) dendrimers possess proinflammatory activities in vivo …

Inclusion bodies (IBs) are protein nanoclusters obtained during recombinant protein
production processes, and several studies have demonstrated their potential as biomaterials …

Oxidative stress and inflammation are basic pathogenic factors involved in tissue injury and
pain, as well as acute and chronic diseases. Since long-term uses of synthetic steroids and …

Systemic Lupus Erythematosus (SLE) is a common and devastating autoimmune disease,
characterized by a dysregulated adaptive immune response against intracellular antigens …

Following infection, HIV establishes reservoirs within tissues that are inaccessible to optimal
levels of antiviral drugs or within cells where HIV lies latent, thus escaping the action of anti …

The approximation of euglycemia is the most effective means of preventing diabetic
complications, which is achieved through effective insulin delivery. Recent reports indicate …

Objective and design The aim of this study was to determine potential effects of gold (+) and
gold (−) nanoparticles, AuNP (+) and AuNP (−), on neutrophil biology. Material or subjects …

Abstract Background Functionalized nanoparticles (NPs) are one promising tool for
detecting specific molecular targets and combine molecular biology and nanotechnology …