Stapled peptides—a useful improvement for peptide-based drugs

M Moiola, MG Memeo, P Quadrelli - Molecules, 2019 - mdpi.com
Peptide-based drugs, despite being relegated as niche pharmaceuticals for years, are now
capturing more and more attention from the scientific community. The main problem for …

Alternative Approach to the Large-Scale Synthesis of the Densely Functionalized Pyrrolidone BMT-415200

S Rakshit, S Sathasivam, R Reddy… - … Process Research & …, 2023 - ACS Publications
The development of a multi-kilogram-scale synthetic route to enantiomerically pure ((2 S, 3
S, 4 S)-3-ethyl-4-fluoro-5-oxopyrrolidin-2-yl) methyl methanesulfonate (BMT-415200) 1 is …

Synthesis and characterization of tetradentate benzophenone derivative Schiff base and properties in different lyotropic media

A Suhta, S Meral, A Alaman Ağar, B Sütay… - … Crystals and Liquid …, 2024 - Taylor & Francis
A new Schiff base ligand of 6, 6′-(1Z, 1′ Z)-(butane-1, 4-diylbis (azanylyidene)) bis (
phenylmethanylylidene)) bis (3-octyloxy) phenol) was synthesized and characterized using …

Synthesis, Voltammetric and Analytical Applications of Some Fluorine Substituted Spirosteroidalthiazolidin‐4‐one Derivatives of Sulfa Drugs

MST Makki, KO Alfooty… - Journal of the …, 2016 - Wiley Online Library
Abstract A new 5‐arylidene‐4‐oxo‐(sulfonamoyl phenyl)‐spiro [thiazolidinone‐2, 2′‐
steroids] series (7–10) was prepared by condensation of sulfanilamide, sulfapyridine and …

Nickel-coordinated chiral enols and Michael addition intermediate stabilized by the Ni–C bond

LA Hayriyan, AF Mkrtchyan, MA Moskalenko… - Mendeleev …, 2018 - Elsevier
A representative within a new class of chiral enol Ni II complexes derived from a Schiff base
of aminoacetone and (S)-2-N-(N-benzylprolinoylamino) benzophenone was prepared, and …

[图书][B] Design and synthesis of chemical probes for investigations into sulforaphane metabolism

A Albulescu - 2022 - search.proquest.com
Abstract Sulforaphane (1: 1-isothiocyanato-4-methylsulfinylbutane), one of several
isothiocyanates (ITCs) that can be isolated from vegetables of the Brassica family, has …