The application of Aptamer in biomarker discovery

Y Li, WW Tam, Y Yu, Z Zhuo, Z Xue, C Tsang, X Qiao… - Biomarker …, 2023 - Springer
Biomarkers are detectable molecules that can reflect specific physiological states of cells,
organs, and organisms and therefore be regarded as indicators for specific diseases. And …

The FOXO family of transcription factors: key molecular players in gastric cancer

Y Liu, X Ao, Y Jia, X Li, Y Wang, J Wang - Journal of Molecular Medicine, 2022 - Springer
Gastric cancer (GC) is the fifth most frequently diagnosed cancer worldwide and the third
leading cause of cancer-related death with an oncological origin. Despite its decline in …

The regulation of PBXs and their emerging role in cancer

Y Liu, X Ao, X Zhou, C Du… - Journal of Cellular and …, 2022 - Wiley Online Library
Pre‐B‐cell leukaemia transcription factor (PBX) proteins are a subfamily of evolutionarily
conserved, atypical homeodomain transcription factors that belong to the superfamily of …

Aptamer-conjugated gold nanoparticles and their diagnostic and therapeutic roles in cancer

G Deng, H Zha, H Luo, Y Zhou - Frontiers in Bioengineering and …, 2023 - frontiersin.org
The burden of incidence rate and mortality of cancer is increasing rapidly, and the
development of precise intervention measures for cancer detection and treatment will help …

[HTML][HTML] Application of P4 (predictive, preventive, personalized, participatory) approach to occupational medicine

G Collatuzzo, P Boffetta - La Medicina del lavoro, 2022 - ncbi.nlm.nih.gov
In recent years there has been a growth in the role of prevention in controlling the disease
burden. Increasing efforts have been conveyed in the screening implementation and public …

Tumor biomarkers for diagnosis, prognosis and targeted therapy

Y Zhou, L Tao, J Qiu, J Xu, X Yang, Y Zhang… - … and Targeted Therapy, 2024 - nature.com
Tumor biomarkers, the substances which are produced by tumors or the body's responses to
tumors during tumorigenesis and progression, have been demonstrated to possess critical …

Mucins as potential biomarkers for early detection of cancer

SK Gautam, P Khan, G Natarajan, P Atri, A Aithal… - Cancers, 2023 - mdpi.com
Simple Summary Early cancer detection is a challenge in treating cancer patients.
Remarkably, carcinomas of the breast, lung, liver, pancreas, ovary, and colon contribute to …

High-confidence cancer patient stratification through multiomics investigation of DNA repair disorders

GV Mkrtchyan, A Veviorskiy, E Izumchenko… - Cell Death & …, 2022 - nature.com
Multiple cancer types have limited targeted therapeutic options, in part due to incomplete
understanding of the molecular processes underlying tumorigenesis and significant intra …

Genetic and molecular characterization of metabolic pathway-based clusters in esophageal squamous cell carcinoma

Z Wang, Y Zhang, X Yang, T Zhang, Z Li, Y Zhong… - Scientific Reports, 2024 - nature.com
Esophageal squamous cell carcinoma (ESCC) is one of the most aggressive types of
squamous cell carcinoma and represents a significant proportion of esophageal cancer …

Activatable dual cancer-related RNA imaging and combined gene-chemotherapy through the target-induced intracellular disassembly of functionalized DNA …

R Jia, Y Wang, W Ma, J Huang, H Sun, B Chen… - Analytical …, 2022 - ACS Publications
The desire for a cancer theranostic system with simultaneously accurate diagnosis and
efficient therapy is undeniably interminable. Heretofore, theranostic systems with simple …