Systematic Review on Cytotoxic and Anticancer Potential of N-Substituted Isatins as Novel Class of Compounds Useful in Multidrug-Resistant Cancer Therapy: In …
AK Gupta, S Tulsyan, M Bharadwaj… - Topics in Current …, 2019 - Springer
As the emergence of resistance to clinical cancer treatments poses a significant problem in
cancer management, there is a constant need to explore novel anticancer agents which …
cancer management, there is a constant need to explore novel anticancer agents which …
Application of 3D-QSAR, pharmacophore, and molecular docking in the molecular design of diarylpyrimidine derivatives as HIV-1 nonnucleoside reverse transcriptase …
G Liu, W Wang, Y Wan, X Ju, S Gu - International journal of molecular …, 2018 - mdpi.com
Diarylpyrimidines (DAPYs), acting as HIV-1 nonnucleoside reverse transcriptase inhibitors
(NNRTIs), have been considered to be one of the most potent drug families in the fight …
(NNRTIs), have been considered to be one of the most potent drug families in the fight …
3D-QSAR and docking studies on ursolic acid derivatives for anticancer activity based on bladder cell line T24 targeting NF-kB pathway inhibition
D Yadav, B Nath Mishra, F Khan - Journal of Biomolecular …, 2019 - Taylor & Francis
Bladder cancer is the common reason for mortality worldwide, and its increasing rate
announces as a significant area of research in drug designing. The side effects and toxicity …
announces as a significant area of research in drug designing. The side effects and toxicity …
Combined 4D-QSAR and target-based approaches for the determination of bioactive Isatin derivatives
The hybrid method of the Electron-Conformational Genetic Algorithm (EC-GA) was used to
determine the pharmacophore groups and to estimate anticancer activity in isatin derivatives …
determine the pharmacophore groups and to estimate anticancer activity in isatin derivatives …
[PDF][PDF] QSAR and docking study of isatin analogues as cytotoxic agents
Computational chemistry is a unique method in the drug discovery process?? Explain Why?.
In this study 109 molecules containing the isatin backbone were subjected to quantitative …
In this study 109 molecules containing the isatin backbone were subjected to quantitative …