Amino acid metabolism in tumor biology and therapy
J Chen, L Cui, S Lu, S Xu - Cell Death & Disease, 2024 - nature.com
Amino acid metabolism plays important roles in tumor biology and tumor therapy.
Accumulating evidence has shown that amino acids contribute to tumorigenesis and tumor …
Accumulating evidence has shown that amino acids contribute to tumorigenesis and tumor …
The application of patient-derived organoid in the research of lung cancer
Lung cancer is the most common cancer and the leading cause of cancer-related death
worldwide. However, mechanisms of its progression remained unclear and new treatments …
worldwide. However, mechanisms of its progression remained unclear and new treatments …
Ionizing radiation-induced mitophagy promotes ferroptosis by increasing intracellular free fatty acids
P Yang, J Li, T Zhang, Y Ren, Q Zhang, R Liu… - Cell Death & …, 2023 - nature.com
Ferroptosis is a type of cell death characterized by the accumulation of intracellular iron and
an increase in hazardous lipid peroxides. Ferroptosis and autophagy are closely related …
an increase in hazardous lipid peroxides. Ferroptosis and autophagy are closely related …
Targeting glutamine metabolism with photodynamic immunotherapy for metastatic tumor eradication
L Zhao, X Rao, R Zheng, C Huang, R Kong… - Journal of Controlled …, 2023 - Elsevier
Immune checkpoint blockade (ICB) has shown significant clinical success, yet its responses
can vary due to immunosuppressive tumor microenvironments. To enhance antitumor …
can vary due to immunosuppressive tumor microenvironments. To enhance antitumor …
[HTML][HTML] Novel insight into metabolic reprogrammming in cancer radioresistance: A promising therapeutic target in radiotherapy
Currently, cancer treatment mainly consists of surgery, radiotherapy, chemotherapy,
immunotherapy, and molecular targeted therapy, of which radiotherapy is one of the major …
immunotherapy, and molecular targeted therapy, of which radiotherapy is one of the major …
Turbulence of glutamine metabolism in pan-cancer prognosis and immune microenvironment
S He, S Zhang, Y Yao, B Xu, Z Niu, F Liao, J Wu… - Frontiers in …, 2022 - frontiersin.org
Introduction Glutamine is characterized as the nutrient required in tumor cells. The study
based on glutamine metabolism aimed to develop a new predictive factor for pan-cancer …
based on glutamine metabolism aimed to develop a new predictive factor for pan-cancer …
[HTML][HTML] Sijunzi Tang improves gefitinib resistance by regulating glutamine metabolism
Z Wang, T Li, R Li, B Cao, S Wang, X Fei, C Li… - Biomedicine & …, 2023 - Elsevier
Lung cancer is a major health concern and significant barrier to human well-being and
social development. Although targeted therapy has shown remarkable progress in the …
social development. Although targeted therapy has shown remarkable progress in the …
Disruption of TIGAR-TAK1 alleviates immunopathology in a murine model of sepsis
D Wang, Y Li, H Yang, X Shen, X Shi, C Li… - Nature …, 2024 - nature.com
Macrophage-orchestrated inflammation contributes to multiple diseases including sepsis.
However, the underlying mechanisms remain to be defined clearly. Here, we show that …
However, the underlying mechanisms remain to be defined clearly. Here, we show that …
[HTML][HTML] Progress in research on the role of amino acid metabolic reprogramming in tumour therapy: A review
D Wang, X Wan - Biomedicine & Pharmacotherapy, 2022 - Elsevier
Malignant tumors are non-communicable diseases that affect human life health and quality
of life. Anti-tumour-related research has also been the focus and difficulty in oncology …
of life. Anti-tumour-related research has also been the focus and difficulty in oncology …
Metabolomics, Transcriptome and Single-Cell RNA Sequencing Analysis of the Metabolic Heterogeneity between Oral Cancer Stem Cells and Differentiated Cancer …
Y Miao, P Wang, J Huang, X Qi, Y Liang, W Zhao… - Cancers, 2024 - mdpi.com
Simple Summary Cancer stem cell have certain metabolic properties that are distinct from
their differentiated counterparts. Our aim is to characterize CSC metabolism in oral cancer …
their differentiated counterparts. Our aim is to characterize CSC metabolism in oral cancer …