Retroviral superinfection resistance
M Nethe, B Berkhout, AC Van der Kuyl - Retrovirology, 2005 - Springer
The retroviral phenomenon of superinfection resistance (SIR) defines an interference
mechanism that is established after primary infection, preventing the infected cell from being …
mechanism that is established after primary infection, preventing the infected cell from being …
Vaccine design for CD8 T lymphocyte responses
RA Koup, DC Douek - Cold Spring …, 2011 - perspectivesinmedicine.cshlp.org
Vaccines are arguably the most powerful medical intervention in the fight against infectious
diseases. The enormity of the global human immunodeficiency virus type 1 (HIV)/acquired …
diseases. The enormity of the global human immunodeficiency virus type 1 (HIV)/acquired …
[图书][B] HIV and the pathogenesis of AIDS.
JA Levy - 1994 - cabidigitallibrary.org
This book grew out of a scientific review, originally published in Microbiological Reviews. It
has been updated and expanded-now citing more than 2100 references (100 pages of the …
has been updated and expanded-now citing more than 2100 references (100 pages of the …
Depletion of circulating natural type 1 interferon-producing cells in HIV-infected AIDS patients
V Soumelis, I Scott, F Gheyas… - Blood, The Journal …, 2001 - ashpublications.org
Natural interferon-α producing cells (IPCs) are a newly characterized blood cell type, which
is the major source of type I interferons in antiviral innate immune responses. The …
is the major source of type I interferons in antiviral innate immune responses. The …
HIV-specific CD8+ T cells exhibit reduced and differentially regulated cytolytic activity in lymphoid tissue
Elimination of lymphoid tissue reservoirs is a key component of HIV eradication strategies.
CD8+ T cells play a critical role in control of HIV, but their functional attributes in lymph …
CD8+ T cells play a critical role in control of HIV, but their functional attributes in lymph …
Suppression of HIV-specific T cell activity by lymph node CD25+ regulatory T cells from HIV-infected individuals
A Kinter, J McNally, L Riggin… - Proceedings of the …, 2007 - National Acad Sciences
CD25+ CD4+ FoxP3+ regulatory T (Treg) cells isolated from the peripheral blood of
asymptomatic HIV-infected individuals have been demonstrated to significantly suppress …
asymptomatic HIV-infected individuals have been demonstrated to significantly suppress …
Higher macrophage inflammatory protein (MIP)-1α and MIP-1β levels from CD8+ T cells are associated with asymptomatic HIV-1 infection
F Cocchi, AL DeVico, R Yarchoan… - Proceedings of the …, 2000 - National Acad Sciences
To test the hypothesis that β-chemokine levels may be relevant to the control of HIV in vivo,
we compared RANTES, MIP-1α, and MIP-1β production from purified CD8+ T cells from 81 …
we compared RANTES, MIP-1α, and MIP-1β production from purified CD8+ T cells from 81 …
The search for the CD8+ cell anti-HIV factor (CAF)
JA Levy - Trends in immunology, 2003 - cell.com
Efforts to control HIV infection have led to the development of several antiretroviral drugs that
can limit virus replication, however, these therapies do not offer a long-term solution to the …
can limit virus replication, however, these therapies do not offer a long-term solution to the …
Inhibition of HIV-1 infection by the β-chemokine MDC
R Pal, A Garzino-Demo, PD Markham, J Burns… - Science, 1997 - science.org
CD8+ T lymphocytes from individuals infected with human immunodeficiency virus–type 1
(HIV-1) secrete a soluble activity that suppresses infection by HIV-1. A protein associated …
(HIV-1) secrete a soluble activity that suppresses infection by HIV-1. A protein associated …
Tim-3 Negatively Regulates Cytotoxicity in Exhausted CD8+ T Cells in HIV Infection
Cytotoxic CD8+ T cells (CTLs) contain virus infections through the release of granules
containing both perforin and granzymes. T cell 'exhaustion'is a hallmark of chronic persistent …
containing both perforin and granzymes. T cell 'exhaustion'is a hallmark of chronic persistent …