Tumors are not only aggregates of malignant cells but also well-organized complex
ecosystems. The immunological components within tumors, termed the tumor immune …

Globally, bone fractures due to osteoporosis occur every 20 s in people aged over 50 years.
The significant healthcare costs required to manage this problem are further exacerbated by …

The extracellular matrix (ECM) and its mechanical properties play an important role in
regulating the cellular responses that occur during tissue regeneration, wound healing, and …

Abstract The three‐dimensional (3D) multicellular platforms prepared by cells or
biomaterials have been widely applied in biomedical fields for the regeneration of complex …

Bone is an extremely dynamic tissue, undergoing continuous remodeling for its whole
lifetime, but its regeneration or augmentation due to bone loss or defects are not always …

With the aim of understanding and recapitulating cellular interactions of hepatocytes in their
physiological microenvironment and to generate an artificial 3D in vitro model, a co-culture …

Natural tissues are composed of ordered architectural organizations of multiple tissue cells.
The spatial distribution of cells is crucial for directing cellular behavior and maintaining …

Impaired or damaged blood vessels can occur at all levels in the hierarchy of vascular
systems from large vasculatures such as arteries and veins to meso‐and microvasculatures …

Collagen hydrogels are widely used for in-vitro experiments and tissue engineering
applications. Their use has been extended due to their biocompatibility with cells and their …

Achieving surface design and control of biomaterial scaffolds with nanometer-or micrometer-
scaled functional films is critical to mimic the unique features of native extracellular matrices …