Brain-derived neurotrophic factor (BDNF) is widely accepted for its involvement in resilience
and antidepressant drug action, is a common genetic locus of risk for mental illnesses, and …

In the past two decades, much evidence has accumulated unequivocally demonstrating that
child abuse and neglect is associated with a marked increase in risk for major psychiatric …

The Biological Effects of Childhood Trauma - Child and Adolescent Psychiatric Clinics Skip to
Main Content Advertisement Child and Adolescent Psychiatric Clinics of North America Log in …

Stress responses and related outcomes vary markedly across individuals. Elucidating the
molecular underpinnings of this variability is of great relevance for developing individualized …

Research into the causes of psychopathology has largely focused on two broad etiologic
factors: genetic vulnerability and environmental stressors. An important role for …

Objective Childhood maltreatment increases risk for psychopathology. For some highly
prevalent disorders (major depression, substance abuse, anxiety disorders, and …

Although the fact that genetic predisposition and environmental exposures interact to shape
development and function of the human brain and, ultimately, the risk of psychiatric …

Mental health disorders often arise as a combination of environmental and genetic factors.
The FKBP5 gene, encoding the GR co-chaperone FKBP51, has been uncovered as a key …

We provide a theoretical and empirical basis for the claim that individual differences exist in
developmental plasticity and that phenotypic plasticity should be a subject of study in its own …

Recent years have seen increased interest in psychopathologies related to trauma
exposure. Specifically, there has been a growing awareness to posttraumatic stress disorder …