A bright future for serial femtosecond crystallography with XFELs
X-ray free electron lasers (XFELs) have the potential to revolutionize macromolecular
structural biology due to the unique combination of spatial coherence, extreme peak …
structural biology due to the unique combination of spatial coherence, extreme peak …
Strategies for sample delivery for femtosecond crystallography
I Martiel, HM Müller-Werkmeister… - Biological …, 2019 - journals.iucr.org
Highly efficient data-collection methods are required for successful macromolecular
crystallography (MX) experiments at X-ray free-electron lasers (XFELs). XFEL beamtime is …
crystallography (MX) experiments at X-ray free-electron lasers (XFELs). XFEL beamtime is …
Pink-beam serial crystallography
Serial X-ray crystallography allows macromolecular structure determination at both X-ray
free electron lasers (XFELs) and, more recently, synchrotron sources. The time resolution for …
free electron lasers (XFELs) and, more recently, synchrotron sources. The time resolution for …
Fast and accurate data collection for macromolecular crystallography using the JUNGFRAU detector
F Leonarski, S Redford, A Mozzanica… - Nature …, 2018 - nature.com
The accuracy of X-ray diffraction data is directly related to how the X-ray detector records
photons. Here we describe the application of a direct-detection charge-integrating pixel …
photons. Here we describe the application of a direct-detection charge-integrating pixel …
The JUNGFRAU detector for applications at synchrotron light sources and XFELs
A Mozzanica, M Andrä, R Barten… - Synchrotron …, 2018 - Taylor & Francis
JUNGFRAU is the pixel detector developed at PSI for SwissFEL [1]. Although the detector
development was driven by the SwissFEL requirements, it was soon realized that such a …
development was driven by the SwissFEL requirements, it was soon realized that such a …
Emerging time-resolved x-ray diffraction approaches for protein dynamics
DR Hekstra - Annual review of biophysics, 2023 - annualreviews.org
Proteins guide the flows of information, energy, and matter that make life possible by
accelerating transport and chemical reactions, by allosterically modulating these reactions …
accelerating transport and chemical reactions, by allosterically modulating these reactions …
Advancements towards the implementation of clinical phase-contrast breast computed tomography at Elettra
Breast computed tomography (BCT) is an emerging application of X-ray tomography in
radiological practice. A few clinical prototypes are under evaluation in hospitals and new …
radiological practice. A few clinical prototypes are under evaluation in hospitals and new …
[PDF][PDF] 1 kHz fixed-target serial crystallography using a multilayer monochromator and an integrating pixel detector
A Tolstikova, M Levantino, O Yefanov, V Hennicke… - IUCrJ, 2019 - journals.iucr.org
Reliable sample delivery and efficient use of limited beam time have remained bottlenecks
for serial crystallography (SX). Using a high-intensity polychromatic X-ray beam in …
for serial crystallography (SX). Using a high-intensity polychromatic X-ray beam in …
Serial femtosecond crystallography of G protein–coupled receptors
B Stauch, V Cherezov - Annual review of biophysics, 2018 - annualreviews.org
G protein–coupled receptors (GPCRs) represent a large superfamily of membrane proteins
that mediate cell signaling and regulate a variety of physiological processes in the human …
that mediate cell signaling and regulate a variety of physiological processes in the human …
[HTML][HTML] JUNGFRAU detector for brighter x-ray sources: Solutions for IT and data science challenges in macromolecular crystallography
F Leonarski, A Mozzanica, M Brückner… - Structural …, 2020 - pubs.aip.org
In this paper, we present a data workflow developed to operate the adJUstiNg Gain detector
FoR the Aramis User station (JUNGFRAU) adaptive gain charge integrating pixel-array …
FoR the Aramis User station (JUNGFRAU) adaptive gain charge integrating pixel-array …