[HTML][HTML] Towards the sustainable discovery and development of new antibiotics
An ever-increasing demand for novel antimicrobials to treat life-threatening infections
caused by the global spread of multidrug-resistant bacterial pathogens stands in stark …
caused by the global spread of multidrug-resistant bacterial pathogens stands in stark …
Insights into the fate of antibiotics in constructed wetland systems: Removal performance and mechanisms
Antibiotics have been recognized as emerging contaminants that are widely distributed and
accumulated in aquatic environment, posing a risk to ecosystem at trace level. Constructed …
accumulated in aquatic environment, posing a risk to ecosystem at trace level. Constructed …
Mastering the Gram-negative bacterial barrier–Chemical approaches to increase bacterial bioavailability of antibiotics
HK Ropponen, R Richter, AKH Hirsch… - Advanced Drug Delivery …, 2021 - Elsevier
To win the battle against resistant, pathogenic bacteria, novel classes of anti-infectives and
targets are urgently needed. Bacterial uptake, distribution, metabolic and efflux pathways of …
targets are urgently needed. Bacterial uptake, distribution, metabolic and efflux pathways of …
Exploring the Potential of Artificial Intelligence for Hydrogel Development—A Short Review
AI and ML have emerged as transformative tools in various scientific domains, including
hydrogel design. This work explores the integration of AI and ML techniques in the realm of …
hydrogel design. This work explores the integration of AI and ML techniques in the realm of …
Functional Materials to Overcome Bacterial Barriers and Models to Advance Their Development
A Bali, MAM Kamal, G Mulla, B Loretz… - Advanced Functional …, 2023 - Wiley Online Library
With the emerging problem of antimicrobial resistance, the world is facing a slow but
dangerous pandemic. While the discovery of novel antibiotics is reaching a nearly …
dangerous pandemic. While the discovery of novel antibiotics is reaching a nearly …
Bone-Adhesive Hydrogel for Effective Inhibition of M. tuberculosis and Osteoblast Regeneration
S Mehnath, M Sathish Kumar, K Chitra… - ACS Infectious …, 2023 - ACS Publications
Currently, bone tuberculosis (TB) treatment largely involves lifelong drug prescriptions and
surgical intervention, resulting in poor quality of life for patients. Therefore, the fabrication of …
surgical intervention, resulting in poor quality of life for patients. Therefore, the fabrication of …
Sensing of antibiotic–bacteria interactions
AA Baranova, AP Tyurin, VA Korshun, VA Alferova - Antibiotics, 2023 - mdpi.com
Sensing of antibiotic–bacteria interactions is an important area of research that has gained
significant attention in recent years. Antibiotic resistance is a major public health concern …
significant attention in recent years. Antibiotic resistance is a major public health concern …
Machine learning for soft and liquid molecular materials
This review discusses three types of soft matter and liquid molecular materials, namely
hydrogels, liquid crystals and gas bubbles in liquids, which are explored with an emergent …
hydrogels, liquid crystals and gas bubbles in liquids, which are explored with an emergent …
Biophysical properties of hydrogels for mimicking tumor extracellular matrix
The extracellular matrix (ECM) is an essential component of the tumor microenvironment. It
plays a critical role in regulating cell-cell and cell-matrix interactions. However, there is lack …
plays a critical role in regulating cell-cell and cell-matrix interactions. However, there is lack …
Extracellular vesicles as novel assay tools to study cellular interactions of anti-infective compounds–A perspective
R Richter, CM Lehr - Advanced Drug Delivery Reviews, 2021 - Elsevier
Sudden outbreaks of novel infectious diseases and the persistent evolution of antimicrobial
resistant pathogens make it necessary to develop specific tools to quickly understand …
resistant pathogens make it necessary to develop specific tools to quickly understand …