Opioid use disorder (OUD) is a chronic relapsing disorder that, whilst initially driven by
activation of brain reward neurocircuits, increasingly engages anti-reward neurocircuits that …

We did a global review to synthesise data on the prevalence, harms, and interventions for
stimulant use, focusing specifically on the use of cocaine and amphetamines. Modelling …

The US mortality rate has gone up three years in a row from 2014 to 2017 (Xu, Murphy,
Kochanek, & Arias, 2016; Murphy, Xu, Kochanek, & Arias, 2018; Kochanek, Murphy, Xu, & …

We summarise the evidence for medicinal uses of opioids, harms related to the extramedical
use of, and dependence on, these drugs, and a wide range of interventions used to address …

Context Supervised injection facilities are harm reduction interventions that allow people
who inject drugs to use previously obtained substances under the supervision of health …

Inclusion health is a service, research, and policy agenda that aims to prevent and redress
health and social inequities among the most vulnerable and excluded populations. We did …

Background Fentanyl and non-pharmaceutical fentanyls (NPFs) have been responsible for
numerous outbreaks of overdoses all over the United States since the 1970s. However …

Policy Points This article reconceptualizes our understanding of the opioid epidemic and
proposes six strategies that address the epidemic's social roots. In order to successfully …

Background and aims The province of British Columbia (BC) Canada has experienced a
rapid increase in illicit drug overdoses and deaths during the last 4 years, with a provincial …

Background Hospitalizations due to medical and surgical complications of substance use
disorder (SUD) are rising. Most hospitals lack systems to treat SUD, and most people with …