After the hurricane: Anti-COVID-19 drugs development, molecular mechanisms of action and future perspectives
HO Khalifa, YM Al Ramahi - International Journal of Molecular Sciences, 2024 - mdpi.com
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is a new coronavirus in
the Coronaviridae family. The COVID-19 pandemic, caused by SARS-CoV-2, has …
the Coronaviridae family. The COVID-19 pandemic, caused by SARS-CoV-2, has …
Paxlovid as a potential treatment for long COVID
MW McCarthy - Expert Opinion on Pharmacotherapy, 2023 - Taylor & Francis
ABSTRACT Introduction On 31 July 2023, the United States Department of Health and
Human Services announced the formation of the Office of Long COVID Research and …
Human Services announced the formation of the Office of Long COVID Research and …
Development and Validation of a High-Performance Liquid Chromatography with Tandem Mass Spectrometry (HPLC-MS/MS) Method for Quantification of Major …
T Komarov, P Karnakova, O Archakova… - Biomedicines, 2023 - mdpi.com
Molnupiravir is an antiviral drug against viral RNA polymerase activity approved by the FDA
for the treatment of COVID-19, which is metabolized to β-D-N4-hydroxycytidine (NHC) in …
for the treatment of COVID-19, which is metabolized to β-D-N4-hydroxycytidine (NHC) in …
[HTML][HTML] Molnupiravir compared to nirmatrelvir/ritonavir for COVID-19 in high-risk patients with haematological malignancy in Europe. A matched-paired analysis from …
Introduction Molnupiravir and nirmatrelvir/ritonavir are antivirals used to prevent progression
to severe SARS-CoV-2 infections and decrease hospitalisation and mortality rates …
to severe SARS-CoV-2 infections and decrease hospitalisation and mortality rates …
Phytoestrogens: Chemistry, potential health benefits, and their medicinal importance
Phytoestrogens, also known as xenoestrogens, are secondary metabolites derived from
plants that have similar structures and biological effects as human estrogens. These …
plants that have similar structures and biological effects as human estrogens. These …
How do we change our approach to COVID with the changing face of disease?
V Apostolopoulos, J Feehan… - Expert Review of Anti …, 2024 - Taylor & Francis
Introduction The emergence of SARS-CoV-2 triggered a global health emergency, causing>
7 million deaths thus far. Limited early knowledge spurred swift research, treatment, and …
7 million deaths thus far. Limited early knowledge spurred swift research, treatment, and …
Multi-spectroscopic, calorimetric and molecular dynamics evaluation on non-classical intercalation of antiviral drug Molnupiravir with DNA
K Pavithra, R Durga Priyadharshini… - Journal of …, 2023 - Taylor & Francis
The interaction of an antiviral drug Molnupiravir (MOL) with calf thymus DNA (CT-DNA) was
investigated using a series of biophysical techniques. A significant hyperchromism with a …
investigated using a series of biophysical techniques. A significant hyperchromism with a …
Regulatory processes involved in clinical trials and intellectual property rights around vaccine development
This chapter explores the critical intersection of regulatory processes and intellectual
property rights (IPR) within the context of vaccine development. With the ongoing global …
property rights (IPR) within the context of vaccine development. With the ongoing global …
White targeted chromatographic screening method of Molnupiravir and its metabolite with degradation kinetics characterization and in-silico toxicity
SARS-CoV-2 virus triggered a worldwide crisis, with world nations putting up massive efforts
to halt its spread. Molnupiravir (MLN) was the first oral, direct-acting antiviral drug approved …
to halt its spread. Molnupiravir (MLN) was the first oral, direct-acting antiviral drug approved …
COVID-19-Triggered Acute Liver Failure and Rhabdomyolysis: A Case Report and Review of the Literature
Y Matsuki, T Sugihara, T Kihara, T Kawakami, T Kitaura… - Viruses, 2023 - mdpi.com
COVID-19 is primarily known for its respiratory tract involvement, often leading to severe
pneumonia and exacerbation of underlying diseases. However, emerging evidence …
pneumonia and exacerbation of underlying diseases. However, emerging evidence …