The increasing prevalence of the metabolic syndrome (MetS) is a threat to global public
health due to its lethal complications. Nonalcoholic fatty liver disease (NAFLD) is the hepatic …

Liver sinusoidal endothelial cells (LSECs) are key players in maintaining hepatic
homeostasis. They also play crucial roles during liver injury by communicating with liver cell …

During liver fibrogenesis, the reciprocal crosstalk among capillarized liver sinusoidal
endothelial cells (LSECs), activated hepatic stellate cells (HSCs), and dysfunctional …

Liver sinusoidal endothelial cells (LSECs) play a pivotal role in maintaining liver
homeostasis and influencing the pathological processes of various liver diseases. However …

A variety of observational studies have demonstrated that coffee, likely acting through
caffeine, improves health outcomes in patients with chronic liver disease. The primary …

The hepatic sinusoids are composed of liver sinusoidal endothelial cells (LSEC), which are
surrounded by hepatic stellate cells (HSC) and contain liver-resident macrophages called …

The growing recognition of the role of the gut microbiome's impact on alcohol-related
diseases, especially in alcohol-associated liver disease, emphasizes the need to …

Vascular liver disorders (VLDs) comprise a wide spectrum of clinical-pathological entities
that primarily affect the hepatic vascular system of both cirrhotic and non-cirrhotic patients …

Background: The prevalence of NAFLD is rapidly increasing. NAFLD can progress to NASH,
fibrosis, cirrhosis, and HCC, which will soon become the main causes of liver …

Background: Aging increases the susceptibility to chronic liver diseases and hastens liver
fibrosis deterioration, but the underlying mechanisms remain partially understood. The aim …