Minimal/measurable residual disease in AML: a consensus document from the European LeukemiaNet MRD Working Party
GJ Schuurhuis, M Heuser, S Freeman… - Blood, The Journal …, 2018 - ashpublications.org
Measurable residual disease (MRD; previously termed minimal residual disease) is an
independent, postdiagnosis, prognostic indicator in acute myeloid leukemia (AML) that is …
independent, postdiagnosis, prognostic indicator in acute myeloid leukemia (AML) that is …
Acute myeloid leukemia: a comprehensive review and 2016 update
I De Kouchkovsky, M Abdul-Hay - Blood cancer journal, 2016 - nature.com
Acute myeloid leukemia (AML) is the most common acute leukemia in adults, with an
incidence of over 20 000 cases per year in the United States alone. Large chromosomal …
incidence of over 20 000 cases per year in the United States alone. Large chromosomal …
Measurable residual disease-guided treatment with azacitidine to prevent haematological relapse in patients with myelodysplastic syndrome and acute myeloid …
Background Monitoring of measurable residual disease (MRD) in patients with advanced
myelodysplastic syndromes (MDS) or acute myeloid leukaemia (AML) who achieve a …
myelodysplastic syndromes (MDS) or acute myeloid leukaemia (AML) who achieve a …
Metabolic reprogramming: the emerging concept and associated therapeutic strategies
GJ Yoshida - Journal of experimental & clinical cancer research, 2015 - Springer
Tumor tissue is composed of cancer cells and surrounding stromal cells with diverse
genetic/epigenetic backgrounds, a situation known as intra-tumoral heterogeneity. Cancer …
genetic/epigenetic backgrounds, a situation known as intra-tumoral heterogeneity. Cancer …
Allogeneic hematopoietic cell transplantation for acute myeloid leukemia: time to move toward a minimal residual disease–based definition of complete remission?
Purpose Patients with acute myeloid leukemia (AML) who are in morphologic complete
remission are typically considered separately from patients with active disease (ie,≥ 5 …
remission are typically considered separately from patients with active disease (ie,≥ 5 …
Acute myeloid leukaemia in adults
F Ferrara, CA Schiffer - The Lancet, 2013 - thelancet.com
The outlook for patients with acute myeloid leukaemia has improved in the past 30 years.
Unlike other cancers, much of this progress is attributable to refinement of supportive …
Unlike other cancers, much of this progress is attributable to refinement of supportive …
Acute myeloid leukemia: 2014 Update on risk‐stratification and management
EH Estey - American journal of hematology, 2014 - Wiley Online Library
Overview: Evidence suggest that even patients aged 70 or above benefit from specific AML
therapy. The fundamental decision in AML then becomes whether to recommend standard …
therapy. The fundamental decision in AML then becomes whether to recommend standard …
Defining minimal residual disease in acute myeloid leukemia: which platforms are ready for “prime time”?
D Grimwade, SD Freeman - … Journal of the American Society of …, 2014 - ashpublications.org
The past 40 years have witnessed major advances in defining the cytogenetic aberrations,
mutational landscape, epigenetic profiles, and expression changes underlying …
mutational landscape, epigenetic profiles, and expression changes underlying …
Significance of minimal residual disease before myeloablative allogeneic hematopoietic cell transplantation for AML in first and second complete remission
RB Walter, SA Buckley, JM Pagel… - Blood, The Journal …, 2013 - ashpublications.org
Minimal residual disease (MRD) before myeloablative hematopoietic cell transplantation
(HCT) is associated with adverse outcome in acute myeloid leukemia (AML) in first complete …
(HCT) is associated with adverse outcome in acute myeloid leukemia (AML) in first complete …
Measurable residual disease at induction redefines partial response in acute myeloid leukemia and stratifies outcomes in patients at standard risk without NPM1 …
Purpose We investigated the effect on outcome of measurable or minimal residual disease
(MRD) status after each induction course to evaluate the extent of its predictive value for …
(MRD) status after each induction course to evaluate the extent of its predictive value for …