Mammalian AMPK is known to be activated by falling cellular energy status, signaled by
rising AMP/ATP and ADP/ATP ratios. We review recent information about how this occurs …

The yeast Saccharomyces cerevisiae has been a favorite organism for pioneering studies
on nutrient-sensing and signaling mechanisms. Many specific nutrient responses have been …

Availability of key nutrients, such as sugars, amino acids, and nitrogen compounds, dictates
the developmental programs and the growth rates of yeast cells. A number of overlapping …

Glucose is the primary source of energy for the budding yeast Saccharomyces cerevisiae.
Although yeast cells can utilize a wide range of carbon sources, presence of glucose …

Protein Ser/Thr phosphatase-1 (PP1) catalyzes the majority of eukaryotic protein
dephosphorylation reactions in a highly regulated and selective manner. Recent studies …

Living cells obtain energy either by oxidizing reduced compounds of organic or mineral
origin or by absorbing light. Whichever energy source is used, some of the energy released …

The SNF1 (sucrose non-fermenting 1)-related protein kinases 1 (SnRKs1) are the plant
orthologs of the budding yeast SNF1 and mammalian AMPK (AMP-activated protein kinase) …

The phosphorylation and dephosphorylation of proteins, catalysed by protein kinases and
phosphatases, is the major mechanism for the transduction of intracellular signals in …

Like all microorganisms, yeast cells spend most of their natural lifetime in a reversible,
quiescent state that is primarily induced by limitation for essential nutrients. Substantial …

Cells of all living organisms contain complex signal transduction networks to ensure that a
wide range of physiological properties are properly adapted to the environmental conditions …