New developments in the biology of fibroblast growth factors

DM Ornitz, N Itoh - WIREs mechanisms of disease, 2022 - Wiley Online Library
The fibroblast growth factor (FGF) family is composed of 18 secreted signaling proteins
consisting of canonical FGFs and endocrine FGFs that activate four receptor tyrosine …

[HTML][HTML] Far beyond anti-angiogenesis: Benefits for anti-basicFGF therapy in cancer

CY Li, KL Kuang, JR Du, B Eymin, T Jia - Biochimica et Biophysica Acta …, 2022 - Elsevier
Basic FGF (bFGF) was discovered as a typical inducer of angiogenesis and has already
been studied for 3 decades. Recent evidence indicates that bFGF plays different roles and …

Enhanced expression of pentraxin-3 in glioblastoma cells correlates with increased invasion and IL8-VEGF signaling axis

UV Wesley, I Sutton, PA Clark, K Cunningham… - Brain research, 2022 - Elsevier
Glioblastoma (GB) is highly invasive and resistant to multimodal treatment partly due to
distorted vasculature and exacerbated inflammation. The aggressiveness of brain tumors …

Long-chain pentraxin 3 possesses agglutination activity and plays a role in host defense against bacterial infection in Oreochromis niloticus

L Qiu, J Li, H Bai, L Wang, Q Zeng, S Wu, P Li… - Developmental & …, 2023 - Elsevier
Abstract Pentraxin 3 (PTX3) is a soluble pattern recognition molecule in the innate immune
system that has multiple functions. It is involved in resisting pathogen infection. However, the …

detectCilia: An R Package for Automated Detection and Length Measurement of Primary Cilia

K Budde-Sagert, S Krueger, C Sehlke… - … and Biology Insights, 2024 - journals.sagepub.com
Background and objective: The primary cilium is a small protrusion found on most
mammalian cells. It acts as a cellular antenna, being involved in various cell signaling …

Pentraxins in invertebrates and vertebrates: From structure, function and evolution to clinical applications

Y Wang, W Chen, S Ding, W Wang, C Wang - … & Comparative Immunology, 2023 - Elsevier
The immune system is divided into two broad categories, consisting of innate and adaptive
immunity. As recognition and effector factors of innate immunity and regulators of adaptive …

Hedgehog/HDAC6 inhibition and chemotherapy: assessment of new drug combination in acute myeloid leukemia

A Pezzotta - 2022 - air.unimi.it
Abstract In Acute Myeloid Leukemia (AML), the dysregulation of the Hh signaling is involved
in the development and expansion of leukemic cancer cells and influences the response to …

Studying the influence of cell culture medium composition on ciliary length with detectCilia: An R package for automated detection and length measurement of primary …

K Budde, S Krueger, C Sehlke, H Lemcke… - Available at SSRN … - papers.ssrn.com
Background and objective: The primary cilium is a cellular protrusion found on most
mammalian cell types. This structure is involved in various cell signaling pathways …

[HTML][HTML] Expression of Fibroblast Growth Factor 4 in a Rat Model of Polydactyly of the Thumb Induced by Cytarabine

X Zhao, W Yang, G Li, H Dong, J Hou… - … Medical Journal of …, 2020 - ncbi.nlm.nih.gov
Expression of Fibroblast Growth Factor 4 in a Rat Model of Polydactyly of the Thumb Induced
by Cytarabine - PMC Back to Top Skip to main content NIH NLM Logo Access keys NCBI …