Performance of nanoparticles for biomedical applications: The in vitro/in vivo discrepancy

S Berger, M Berger, C Bantz, M Maskos… - Biophysics Reviews, 2022 - pubs.aip.org
Nanomedicine has a great potential to revolutionize the therapeutic landscape. However, up-
to-date results obtained from in vitro experiments predict the in vivo performance of …

How to xenograft cancer cells on the chorioallantoic membrane of a fertilized hen's egg and its visualization by PET/CT and MRI

J Schulze, D Librizzi, L Bender, J Jedelská… - ACS applied bio …, 2023 - ACS Publications
The chorioallantoic membrane (CAM) of fertilized hen's eggs represents a unique and
alternative model for cancer research. The CAM model provides an optimal platform for …

Photoactive Parietin-loaded nanocarriers as an efficient therapeutic platform against triple-negative breast cancer

AM Ayoub, MS Atya, AM Abdelsalam, J Schulze… - International journal of …, 2023 - Elsevier
The application of photodynamic therapy has become more and more important in
combating cancer. However, the high lipophilic nature of most photosensitizers limits their …

[HTML][HTML] Evaluating the photodynamic efficacy of nebulized curcumin-loaded liposomes prepared by thin-film hydration and dual centrifugation: In vitro and in ovo …

L Bender, AM Ayoub, J Schulze, MU Amin… - Biomaterials …, 2024 - Elsevier
Lung cancer, one of the most common causes of high mortality worldwide, still lacks
appropriate and convenient treatment options. Photodynamic therapy (PDT) has shown …

Enhanced photodynamic therapy of curcumin using biodegradable PLGA coated mesoporous silica nanoparticles

MU Amin, S Ali, KH Engelhardt, U Nasrullah… - European Journal of …, 2024 - Elsevier
Since the available treatments are not highly effective to combat cancer, therefore, the
alternative strategies are unavoidable. Photodynamic therapy (PDT) is one of the emerging …

Modern Photodynamic Glioblastoma Therapy Using Curcumin-or Parietin-Loaded Lipid Nanoparticles in a CAM Model Study

J Schulze, L Schöne, AM Ayoub… - ACS Applied Bio …, 2023 - ACS Publications
Natural photosensitizers, such as curcumin or parietin, play a vital role in photodynamic
therapy (PDT), causing a light-mediated reaction that kills cancer cells. PDT is a promising …

Leucocyte membrane camouflaged poly-lactic-co-glycolic acid (PLGA) nanoparticles containing cannabidiol and paclitaxel against breast cancer therapy

A Nadaf, N Hasan, S Ahmad, A Gupta, D Jain… - Process …, 2024 - Elsevier
The current investigation focuses on developing multi-drug-loaded poly-lactic-co-glycolic
acid (PLGA) nanoparticles clothed with leucocyte membrane. Firstly, Paclitaxel (PTX) and …

[HTML][HTML] In vitro and in ovo photodynamic efficacy of nebulized curcumin-loaded tetraether lipid liposomes prepared by DC as stable drug delivery system

L Bender, E Preis, KH Engelhardt, MU Amin… - European Journal of …, 2024 - Elsevier
Lung cancer is one of the most common causes of high mortality worldwide. Current
treatment strategies, eg, surgery, radiotherapy, chemotherapy, and immunotherapy …

Highly stable liposomes based on Tetraether lipids as a promising and versatile drug delivery system

A Hemetsberger, E Preis, K Engelhardt, B Gutberlet… - Materials, 2022 - mdpi.com
Conventional liposomes often lack stability, limiting their applicability and usage apart from
intravenous routes. Nevertheless, their advantages in drug encapsulation and …

[PDF][PDF] Precise aminoethylene-based nanocarriers for dynamic nucleic acid delivery: A balancing act between polyplex stability and cargo release

S Berger - 2023 - edoc.ub.uni-muenchen.de
Therapeutic intervention at the genomic level offers various options for the preventive or
causal treatment of severe and life-threatening diseases such as viral infections, cancer, or …