Overcoming barriers in photodynamic therapy harnessing nano-formulation strategies
Photodynamic therapy (PDT) has been extensively investigated for decades for tumor
treatment because of its non-invasiveness, spatiotemporal selectivity, lower side-effects, and …
treatment because of its non-invasiveness, spatiotemporal selectivity, lower side-effects, and …
[HTML][HTML] Emerging strategies in enhancing singlet oxygen generation of nano-photosensitizers toward advanced phototherapy
The great promise of photodynamic therapy (PDT) has thrusted the rapid progress of
developing highly effective photosensitizers (PS) in killing cancerous cells and bacteria. To …
developing highly effective photosensitizers (PS) in killing cancerous cells and bacteria. To …
GSH-responsive nanoprodrug to inhibit glycolysis and alleviate immunosuppression for cancer therapy
X Liu, Y Li, K Wang, Y Chen, M Shi, X Zhang… - Nano Letters, 2021 - ACS Publications
Blocking energy metabolism of cancer cells and simultaneously stimulating the immune
system to perform immune attack are significant for cancer treatment. However, how to …
system to perform immune attack are significant for cancer treatment. However, how to …
Aggregation-induced emission-active micelles: synthesis, characterization, and applications
Y Liu, X Chen, X Liu, W Guan, C Lu - Chemical Society Reviews, 2023 - pubs.rsc.org
Aggregation-induced emission (AIE)-active micelles are a type of fluorescent functional
materials that exhibit enhanced emissions in the aggregated surfactant state. They have …
materials that exhibit enhanced emissions in the aggregated surfactant state. They have …
[HTML][HTML] Antimicrobial photodynamic therapy: Latest developments with a focus on combinatory strategies
R Youf, M Müller, A Balasini, F Thétiot, M Müller… - Pharmaceutics, 2021 - mdpi.com
Antimicrobial photodynamic therapy (aPDT) has become a fundamental tool in modern
therapeutics, notably due to the expanding versatility of photosensitizers (PSs) and the …
therapeutics, notably due to the expanding versatility of photosensitizers (PSs) and the …
[HTML][HTML] Stimulus-responsive self-assembled prodrugs in cancer therapy
Small-molecule prodrugs have become the main toolbox to improve the unfavorable
physicochemical properties of potential therapeutic compounds in contemporary anti-cancer …
physicochemical properties of potential therapeutic compounds in contemporary anti-cancer …
Deep downregulation of PD‐L1 by caged peptide‐conjugated AIEgen/miR‐140 nanoparticles for enhanced immunotherapy
J Dai, JJ Hu, X Dong, B Chen, X Dong… - Angewandte Chemie …, 2022 - Wiley Online Library
Downregulating programmed cell death ligand 1 (PD‐L1) protein levels in tumor cells is an
effective way to achieve immune system activation for oncology treatment, but current …
effective way to achieve immune system activation for oncology treatment, but current …
Enhanced chemo-photodynamic therapy of an enzyme-responsive prodrug in bladder cancer patient-derived xenograft models
P Tan, H Cai, Q Wei, X Tang, Q Zhang, M Kopytynski… - Biomaterials, 2021 - Elsevier
Patient-derived xenograft (PDX) models are powerful tools for understanding cancer biology
and drug discovery. In this study, a polymeric nano-sized drug delivery system poly …
and drug discovery. In this study, a polymeric nano-sized drug delivery system poly …
Nanoscale covalent organic frameworks with donor–acceptor structure for enhanced photothermal ablation of tumors
Covalent organic frameworks (COFs) have shown great potential in catalysis and the
biomedical fields, but monodisperse COFs with tunable sizes are hard to obtain. Herein, we …
biomedical fields, but monodisperse COFs with tunable sizes are hard to obtain. Herein, we …
Nanotherapeutic intervention in photodynamic therapy for cancer
The clinical need for photodynamic therapy (PDT) has been growing for several decades.
Notably, PDT is often used in oncology to treat a variety of tumors since it is a low-risk …
Notably, PDT is often used in oncology to treat a variety of tumors since it is a low-risk …