Mechanical and biological interactions of implants with the brain and their impact on implant design
D Prodanov, J Delbeke - Frontiers in neuroscience, 2016 - frontiersin.org
Neural prostheses have already a long history and yet the cochlear implant remains the only
success story about a longterm sensory function restoration. On the other hand, neural …
success story about a longterm sensory function restoration. On the other hand, neural …
Invasive intraneural interfaces: foreign body reaction issues
Intraneural interfaces are stimulation/registration devices designed to couple the peripheral
nervous system (PNS) with the environment. Over the last years, their use has increased in a …
nervous system (PNS) with the environment. Over the last years, their use has increased in a …
A survey of fractional-order circuit models for biology and biomedicine
TJ Freeborn - IEEE Journal on emerging and selected topics in …, 2013 - ieeexplore.ieee.org
In this survey, we present many of the fractional-order circuit models used in biomedicine
and biology to fit experimentally collected impedance data. An overview of the different …
and biology to fit experimentally collected impedance data. An overview of the different …
Comprehensive characterization and failure modes of tungsten microwire arrays in chronic neural implants
For nearly 55 years, tungsten microwires have been widely used in neurophysiological
experiments in animal models to chronically record neuronal activity. While tungsten …
experiments in animal models to chronically record neuronal activity. While tungsten …
Implant size and fixation mode strongly influence tissue reactions in the CNS
The function of chronic brain machine interfaces depends on stable electrical contact
between neurons and electrodes. A key step in the development of interfaces is therefore to …
between neurons and electrodes. A key step in the development of interfaces is therefore to …
Abiotic-biotic characterization of Pt/Ir microelectrode arrays in chronic implants
Pt/Ir electrodes have been extensively used in neurophysiology research in recent years as
they provide a more inert recording surface as compared to tungsten or stainless steel …
they provide a more inert recording surface as compared to tungsten or stainless steel …
Quantifying long-term microelectrode array functionality using chronic in vivo impedance testing
A Prasad, JC Sanchez - Journal of neural engineering, 2012 - iopscience.iop.org
Long-term acquisition of high-quality neural recordings is a cornerstone of neuroprosthetic
system design. Mitigating the experimental variability of chronically implanted arrays has …
system design. Mitigating the experimental variability of chronically implanted arrays has …
Long-term changes in the material properties of brain tissue at the implant–tissue interface
A Sridharan, SD Rajan… - Journal of neural …, 2013 - iopscience.iop.org
Objective. Brain tissue undergoes dramatic molecular and cellular remodeling at the implant–
tissue interface that evolves over a period of weeks after implantation. The biomechanical …
tissue interface that evolves over a period of weeks after implantation. The biomechanical …
The density difference between tissue and neural probes is a key factor for glial scarring
G Lind, CE Linsmeier, J Schouenborg - Scientific reports, 2013 - nature.com
A key to successful chronic neural interfacing is to achieve minimal glial scarring
surrounding the implants, as the astrocytes and microglia may functionally insulate the …
surrounding the implants, as the astrocytes and microglia may functionally insulate the …
Correlations between histology and neuronal activity recorded by microelectrodes implanted chronically in the cerebral cortex
D McCreery, S Cogan, S Kane… - Journal of neural …, 2016 - iopscience.iop.org
Objective. To quantify relations between the neuronal activity recorded with chronically-
implanted intracortical microelectrodes and the histology of the surrounding tissue, using …
implanted intracortical microelectrodes and the histology of the surrounding tissue, using …